Distribution of oculocutaneous albinism in Zimbabwe
Distribution of oculocutaneous albinism in Zimbabwe
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DOI：
10.1136/jmg.33.8.641
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发表时间：
1996-08-01
影响因子：
4
通讯作者：
Lund, PM
中科院分区：
文献类型：
--
作者：
Lund, PM
一项对津巴布韦130万名学童的调查发现，共有278名学生患有眼皮肤白化病（OCA），患病率为1/4728。全国各省均有OCA患儿，但分布不均匀。在某些地区，特别是在首都哈拉雷和马尼卡兰的东部省，发生率明显高于其他地区。虽然大多数白化病学生属于占多数的绍纳族，但在该国少数民族中也发现了OCA患者。农村学生患白化病的人数是城市学生的2倍（248比129），但城市学生的OCA患病率明显高于农村学生。地区这些结果表明，仅在城市地区收集的国家数据可能有偏差，并强调需要为受影响的人广泛分布卫生和特殊教育设施。
A survey of 1.3 million schoolchildren in Zimbabwe identified a total of 278 pupils with oculocutaneous albinism (OCA), giving a prevalence of 1 in 4728. Pupils with OCA were identified in every province of the country, bur the distribution was not even. In certain areas, notably the capital, Harare, and the eastern province of Manicaland, the frequency was significantly higher than in others. Although most of the pupils with albinism belonged to the majority Shona ethnic group, people with OCA were also found among the minority population groups in the country. There were almost twice as many pupils with albinism in rural compared with urban schools (248 v 129), However, the prevalence of OCA was significantly higher in urban than rural. areas. These results indicate that data for a country collected solely in urban locations are likely to be biased and emphasise the need for widespread distribution of health and special educational facilities for affected people.