Development and evaluation of a linear staircase strategy for the measurement of perimetric sensitivity
Development and evaluation of a linear staircase strategy for the measurement of perimetric sensitivity
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DOI：
10.1016/j.visres.2006.03.004
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发表时间：
2006-09-01
期刊：
影响因子：
1.8
通讯作者：
Garway-Heath, David F.
中科院分区：
文献类型：
--
作者：
Malik, Rizwan;Swanson, William H.;Garway-Heath, David F.
青光眼患者的周边敏感性传统上以对数（dB）单位测量，但线性敏感性与青光眼损伤的传统结构测量更好地相关。周长算法的Monte Carlo模拟用于评估当周长灵敏度以线性单位表示时对数步长对偏倚和变异性的潜在影响，并评估使用线性步长的算法的潜在受益。模拟结果表明，线性阶梯可以降低偏倚、变异性和效率的灵敏度依赖性。这些预测得到了对21例青光眼患者和20例年龄相似的对照者进行的外周研究的支持，这些患者在几周内重复就诊。(c)2006爱思唯尔有限公司保留所有权利。
Perimetric sensitivity of patients with glaucoma has traditionally been measured in logarithmic (dB) units, but linear sensitivity correlates better with conventional structural measures of glaucomatous damage. Monte Carlo simulations of perimetric algorithms were used to assess potential effects of logarithmic steps on bias and variability when perimetric sensitivity was represented in linear units, and to assess the potential benefits of algorithms using linear steps. Simulations predicted that linear staircases could reduce the sensitivity-dependence of bias, variability and efficiency. These predictions were supported by a perimetric study of 21 patients with glaucoma and 20 age-similar controls who made repeat visits over several weeks. (c) 2006 Elsevier Ltd. All rights reserved.