Relationship between histologic thickness of tongue carcinoma and thickness estimated from preoperative MRI
Relationship between histologic thickness of tongue carcinoma and thickness estimated from preoperative MRI
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DOI：
10.1007/s00330-006-0263-9
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发表时间：
2006-10-01
影响因子：
5.9
通讯作者：
Bellomi, Massimo
中科院分区：
文献类型：
--
作者：
Preda, Lorenzo;Chiesa, Fausto;Bellomi, Massimo
一些研究表明，舌癌的厚度与预后和颈淋巴结转移的可能性有关。我们研究了术前对肿瘤厚度和体积的估计，如通过磁共振成像（MRI）确定的，是否与组织学厚度相关，从而可能预测颈部转移的存在。我们对33例舌鳞状细胞癌患者的回顾性研究中，评估了组织学肿瘤厚度与MRI肿瘤厚度和体积之间的关系。通过直接测量和考虑溃疡或肿瘤赘生物校正（重建厚度）确定厚度。MRI厚度和同侧和对侧淋巴结转移的存在或不存在之间的关系也进行了研究。我们发现MRI厚度与组织学肿瘤厚度密切相关，尽管平均MRI厚度显著大于组织学厚度。对侧颈部受累患者的MRI厚度显著大于无颈部受累患者。我们的结论是，MRI提供了一个准确的和可重复的方法来估计舌癌的厚度，铺平了道路，为进一步研究更广泛的一系列患者，以确定术前确定的MRI厚度是否可以可靠地预测同侧和双侧颈部参与。
Several studies have shown that the thickness of tongue carcinoma is related to prognosis and to the likelihood of cervical node metastases. We investigated whether preoperative estimates of tumor thickness and volume, as determined from magnetic resonance imaging (MRI), correlated with histologic thickness and might therefore predict the presence of neck metastases. We assessed relationships between histologic tumor thickness and MRI tumor thickness and volume in a retrospective series of 33 patients with squamous cell carcinoma of the tongue. Thicknesses were determined by direct measurement and by considering corrections for ulceration or tumor vegetation (reconstructed thickness). Relationships between MRI thickness and the presence or absence of homolateral and contralateral nodal metastases were also investigated. We found that MRI thicknesses correlated strongly and directly with histologic tumor thicknesses, although mean MRI thicknesses were significantly greater than histologic thicknesses. MRI thicknesses were significantly greater in patients with contralateral neck involvement than in those with no neck involvement. We conclude that MRI provides an accurate and reproducible means of estimating the thickness of tongue carcinomas, paving the way for further studies on more extensive series of patients to determine whether preoperatively determined MRI thickness can reliably predict homolateral and bilateral neck involvement.