HIV plus deceased donor referrals: A national survey of organ procurement organizations
HIV plus deceased donor referrals: A national survey of organ procurement organizations
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DOI：
10.1111/ctr.13171
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发表时间：
2018-02-01
影响因子：
2.1
通讯作者：
Durand, Christine M.
中科院分区：
文献类型：
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作者：
Cash, Ayla;Luo, Xun;Durand, Christine M.
根据《艾滋病毒器官政策公平（HOPE）法案》，感染艾滋病毒（HIV+）的供体器官可以移植到艾滋病毒+受体体内。量化器官采购组织（opo）收到的艾滋病毒阳性供体转诊对《希望法案》的实施至关重要。方法对美国58家opo的HIV+转诊记录和新发现的HIV+献血者进行调查。利用opo提供的准确记录和CDC艾滋病毒流行率数据，我们预测了全国艾滋病毒阳性转诊的估计。结果55家（95%）opo每年报告HIV阳性病例0 ~ 276例，新发现HIV阳性病例0 ~ 10例。艾滋病毒高流行地区的6个门诊诊所报告了100多例艾滋病毒阳性供体转诊。27家（47%）opo提供了准确的HIV+转诊记录，28家（51%）opo提供了发现HIV+病例的准确记录，上一年共有1450例HIV+转诊和39例发现HIV+献血者。这些opo分别占美国流行艾滋病毒病例的67%和59%；因此，我们估计全国每年有2164例HIV+转诊病例和66例发现的HIV+病例。结论sopo每年报告了大量HIV+转诊，其中一部分患者在医学上符合捐献条件。特别是在艾滋病毒流行率高的地区，ops需要持续的支持来执行《希望法案》。
BackgroundHIV-infected (HIV+) donor organs can be transplanted into HIV+ recipients under the HIV Organ Policy Equity (HOPE) Act. Quantifying HIV+ donor referrals received by organ procurement organizations (OPOs) is critical for HOPE Act implementation.MethodsWe surveyed the 58 USA OPOs regarding HIV+ referral records and newly discovered HIV+ donors. Using data from OPOs that provided exact records and CDC HIV prevalence data, we projected a national estimate of HIV+ referrals.ResultsFifty-five (95%) OPOs reported HIV+ referrals ranging from 0 to 276 and newly discovered HIV+ cases ranging from 0 to 10 annually. Six OPOs in areas of high HIV prevalence reported more than 100 HIV+ donor referrals. Twenty-seven (47%) OPOs provided exact HIV+ referral records and 28 (51%) OPOs provided exact records of discovered HIV+ cases, totaling 1450 HIV+ referrals and 39 discovered HIV+ donors in the prior year. These OPOs represented 67% and 59% of prevalent HIV cases in the USA; thus, we estimated 2164 HIV+ referrals and 66 discovered HIV+ cases nationally per year.ConclusionsOPOs reported a high volume of HIV+ referrals annually, of which a subset will be medically eligible for donation. Particularly in areas of high HIV prevalence, OPOs require ongoing support to implement the HOPE Act.