Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues
Fluorescent probe for highly selective and sensitive detection of hydrogen sulfide in living cells and cardiac tissues
复制标题
用于高选择性和灵敏检测活细胞和心脏组织中硫化氢的荧光探针
DOI:
10.1039/c2an36113b
复制
发表时间:
2013-01-01
期刊:
影响因子:
4.2
通讯作者:
Tang, Xinjing
中科院分区:
文献类型:
--
作者:
Chen, Bifeng;Li, Wei;Tang, Xinjing
A coumarin-based fluorescence chemoprobe was developed and evaluated for the selective and sensitive detection of hydrogen sulfide in degassed PBS buffers and fetal bovine serum. Fluorescence detection of hydrogen sulfide in living cells was also successfully achieved using two-photon confocal fluorescence imaging. Further in situ visualization of endogenous H2S was realized in cardiac tissues of normal rats and atherosclerosis (AS) rats.