Representation of Geometric Borders in the Entorhinal Cortex
Representation of Geometric Borders in the Entorhinal Cortex
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DOI：
10.1126/science.1166466
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发表时间：
2008-12-19
期刊：
影响因子：
56.9
通讯作者：
Moser, Edvard I.
中科院分区：
文献类型：
--
作者：
Solstad, Trygve;Boccara, Charlotte N.;Moser, Edvard I.
我们报告存在的内嗅细胞类型，火灾时，动物是接近边界的近端环境。当环境被拉伸时以及在不同房间中的不同尺寸和形状的封闭物中测试期间，这些“边界细胞”的定向特异性边缘贴附活动得以维持。边缘细胞相对稀疏，占局部细胞群的不到10%，但可以在内侧内嗅皮层的所有层以及相邻的旁丘中发现，通常与头向细胞和网格细胞混合。边界单元可以有助于规划轨迹和锚定网格场，并将场放置到几何参考系。
We report the existence of an entorhinal cell type that fires when an animal is close to the borders of the proximal environment. The orientation- specific edge- apposing activity of these " border cells" is maintained when the environment is stretched and during testing in enclosures of different size and shape in different rooms. Border cells are relatively sparse, making up less than 10% of the local cell population, but can be found in all layers of the medial entorhinal cortex as well as the adjacent parasubiculum, often intermingled with head- direction cells and grid cells. Border cells may be instrumental in planning trajectories and anchoring grid fields and place fields to a geometric reference frame.