Upper-Limb Recovery After Stroke: A Randomized Controlled Trial Comparing EMG-Triggered, Cyclic, and Sensory Electrical Stimulation.

Upper-Limb Recovery After Stroke: A Randomized Controlled Trial Comparing EMG-Triggered, Cyclic, and Sensory Electrical Stimulation.
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DOI:
10.1177/1545968316650278
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发表时间:
2016-11
影响因子:
4.2
通讯作者:
Chae J
Chae J
中科院分区:
医学1区
文献类型:
--
作者:
Wilson RD;Page SJ;Delahanty M;Knutson JS;Gunzler DD;Sheffler LR;Chae J

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本研究比较了周期性神经肌肉电刺激(NMES)、肌电图(EMG)触发的NMES和感觉刺激对上肢偏瘫患者运动障碍和活动受限的影响。一项多中心、单盲、多臂平行组研究,研究对象为卒中后6个月内未住院的偏瘫卒中幸存者。122名受试者随机接受周期性NMES、EMG触发的NMES或感觉刺激,每个工作日两次,每次40分钟,持续8周。受试者在治疗结束后随访6个月。所有三组的Fugyl-Meyer评估(F(1,111)=92.6,p<0.001)、Fugyl-Meyer腕和手评估(F(1,111)=66.7,p<0.001)和改良手臂运动能力测试(时间效应,F(1,111)=91.0,p<0.001)均显著增加。在Fugl-Meyer评估(F(2,384)= 0.2,p =0.83)、Fugl-Meyer腕和手评估(F(2,384)= 0.4,p =0.70)或改良手臂运动能力测试(F(2,379)= 1.2,p =0.31)中,各组之间的改善无显著差异。所有组在卒中后6个月内应用电刺激治疗后,损伤和功能限制均显著改善。改善可能是由于自发恢复。基于给予的电刺激类型,没有差异。
This study compared the effect of cyclic neuromuscular electrical stimulation (NMES), electromyography (EMG)-triggered NMES, and sensory stimulation on motor impairment and activity limitations in patients with upper limb hemiplegia. A multicenter, single-blind, multi-arm parallel-group study of non-hospitalized hemiplegic stroke survivors within 6 months of stroke. 122 subjects were randomized to receive either cyclic NMES, EMG triggered NMES, or sensory stimulation twice every weekday in 40-minute sessions, over an 8 week-period. Subjects were followed for 6 months after treatment concluded. There were significant increases in the Fugl-Meyer Assessment (F(1,111)=92.6, p<0.001), Fugyl-Meyer Assessment Wrist and Hand (F(1,111)=66.7, p<0.001), and modified Arm Motor Ability Test (time effect, F(1,111)=91.0, p<0.001) for all three groups. There was not a significant difference in the improvement among groups in the Fugl-Meyer Assessment (F(2,384) = 0.2, p =0.83), Fugl-Meyer Assessment Wrist and Hand (F(2,384) = 0.4, p =0.70), or the modified Arm Motor Ability Test (F(2,379) = 1.2, p =0.31). All groups exhibited significant improvement of impairment and functional limitation with electrical stimulation therapy applied within 6 months of stroke. Improvements were likely due to spontaneous recovery. There was not a difference based on the type of electrical stimulation that was administered.
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期刊: STROKE
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