Psychological factors in prurigo nodularis in comparison with psoriasis vulgaris:: results of a case-control study
Psychological factors in prurigo nodularis in comparison with psoriasis vulgaris:: results of a case-control study
复制标题
DOI：
10.1111/j.1365-2133.2005.06852.x
复制
发表时间：
2006-01-01
影响因子：
10.3
通讯作者：
Heuft, G
中科院分区：
文献类型：
--
作者：
Schneider, G;Hockmann, J;Heuft, G
研究背景：抑制愤怒和利他主义的人际行为等心理因素可能在结节性黑热病（PN）慢性瘙痒的病因学中起作用。目的探讨PN患者与银屑病患者的心身问题领域及精神共病性。方法对94例PN患者和91例银屑病患者进行医院焦虑抑郁量表、多伦多述情障碍量表、焦虑抑郁量表、状态-特质愤怒表达量表、人际关系问题量表、躯体形式障碍筛查和Whiteley指数用于hypotherapyasis.Results结果经Bonferroni事后校正后，PN患者和银屑病患者的测量量表无显著差异。PN患者只有较少的“愤怒”和较少的专制/支配和更多的不安全/顺从行为的倾向。PN患者，在一般情况下，可比与银屑病方面的述情障碍，躯体化症状，抑郁症，焦虑和抑郁症，18%的情况下，焦虑和22%cases of depression.Conclusions的假设制定在文献中的PN的具体病因不能被证明为大多数PN患者在我们的研究。在精神病理学方面，PN患者与银屑病患者相似。因此，PN的临床管理应包括心身评估。
Background It has been suggested that psychological factors such as repressing anger and altruistic interpersonal behaviour may play a role in the aetiology of chronic itching in prurigo nodularis (PN). Whether these issues are specific for PN or are also common in other chronic skin diseases, e.g. psoriasis, has not been investigated until now.Objectives To investigate psychosomatic problem areas and psychiatric comorbidity in patients with PN in comparison with patients with psoriasis.Methods Ninety-four patients with PN and 91 patients with psoriasis were administered the Hospital Anxiety and Depression Scale, Toronto Alexithymia Scale, State-Trait Anger Expression Inventory, Inventory of Interpersonal Problems, Screening for Somatoform Disorders and the Whiteley Index for hypochondriasis.Results After Bonferroni post hoc adjustment, the metrical scales demonstrated no significant differences between patients with PN and those with psoriasis. There was only a tendency to less 'anger-out' and to less autocratic/dominant and more insecure/submissive behaviour in the patients with PN. Patients with PN were, in general, comparable with those with psoriasis with regard to alexithymia, somatization symptoms, hypochondriasis, anxiety and depression, with 18% cases of anxiety and 22% cases of depression.Conclusions The hypotheses formulated in the literature on the specific aetiology of PN could not be proven for the majority of patients with PN in our study. Concerning their psychopathology, patients with PN were comparable with those with psoriasis. Therefore the clinical management of PN should include psychosomatic assessment.