Using chronic recordings from a closed-loop neurostimulation system to capture seizures across multiple thalamic nuclei.
Using chronic recordings from a closed-loop neurostimulation system to capture seizures across multiple thalamic nuclei.
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DOI:
10.1002/acn3.51701
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发表时间:
2023-01
影响因子:
5.3
通讯作者:
Rolston, John D.
中科院分区:
文献类型:
--
作者:
Kundu, Bornali;Arain, Amir;Davis, Tyler;Charlebois, Chantel M.;Rolston, John D.
We report the case of a patient with unilateral diffuse frontotemporal epilepsy in whom we implanted a responsive neurostimulation system with leads spanning the anterior and centromedian nucleus of the thalamus. During chronic recording, ictal activity in the centromedian nucleus consistently preceded the anterior nucleus, implying a temporally organized seizure network involving the thalamus. With stimulation, the patient had resolution of focal impaired awareness seizures and secondarily generalized seizures. This report describes chronic recordings of seizure activity from multiple thalamic nuclei within a hemisphere and demonstrates the potential efficacy of closed‐loop neurostimulation of multiple thalamic nuclei to control seizures.
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