Magnetic resonance evaluation of the interrelationship between articular cartilage and trabecular bone of the osteoarthritic knee
Magnetic resonance evaluation of the interrelationship between articular cartilage and trabecular bone of the osteoarthritic knee
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DOI：
10.1016/j.joca.2003.10.009
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发表时间：
2004-02-01
影响因子：
7
通讯作者：
Majumdar, S
中科院分区：
文献类型：
--
作者：
Lindsey, CT;Narasimhan, A;Majumdar, S
目的：目的：应用高分辨磁共振成像（MRI）技术研究膝关节骨性关节炎（OA）患者股骨、髁状突和胫骨骨小梁改变与关节软骨退变的关系。在1.5T下获得膝关节的STEM图像（0.234x0.234 mm（2），2 mm层厚），并用于计算股骨和胫骨软骨的体积和厚度。采用轴位图像（0.1954.195 mm 2，层厚1 mm）计算骨小梁结构参数：表观骨体积分数、骨小梁数量、骨小梁间距和骨小梁厚度。结果：OA患者的骨小梁体积和厚度均小于正常对照组（P
Objective: To use high-resolution magnetic resonance imaging (MRI) to determine the relationship between articular cartilage degeneration and trabecular bone changes of the femur, condyles and tibia in human knees with osteoarthritis (OA).Methods: Subjects were divided into three groups: without OA (OA0), mild OA (OA1) and severe OA (OA2). Sagittal images of the knee (0.234x0.234 mm(2), 2-mm slice thickness) were obtained at 1.5T and used for calculating the volume and thickness of the femoral and tibial cartilage. Axial images (0.1954.195 mm(2), 1-mm slice thickness) were used for calculating the trabecular bone structure parameters: apparent bone volume fraction, trabecular number, trabecular separation and trabecular thickness.Results: Cartilage volume and thickness were less in patients with OA compared to normal controls (P