Nrf2: a potential target for new therapeutics in liver disease.
Nrf2: a potential target for new therapeutics in liver disease.
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DOI:
10.1038/clpt.2012.110
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发表时间:
2012-09
影响因子:
6.7
通讯作者:
中科院分区:
文献类型:
--
作者:
Nuclear erythroid 2–related factor 2 (Nrf2) is an oxidative stress–mediated transcription factor with a variety of downstream targets aimed at cytoprotection. Nrf2 has recently been implicated as a new therapeutic target for the treatment of liver disease. Here, we focus on the most common liver diseases—nonalcoholic fatty liver disease/steatohepatitis, alcoholic liver disease, and drug-induced liver injury—and highlight areas in the development of these conditions where activation of Nrf2 may alleviate disease progression.
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影响因子:
3
作者:
Haugen, E;Nath, KA
通讯作者:
Nath, KA
DOI:
10.1016/j.bbagen.2011.09.018
发表时间:
2012-02-01
影响因子:
3
作者:
Aldaba-Muruato, Liseth R.;Moreno, Mario G.;Muriel, Pablo
通讯作者:
Muriel, Pablo
DOI:
10.1016/s0167-4781(00)00238-4
发表时间:
2000-12-15
期刊:
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
影响因子:
--
作者:
Chan, JY;Kwong, M
通讯作者:
Kwong, M
影响因子:
2.6
作者:
Cordova, E. J.;Velazquez-Cruz, R.;Orozco, L.
通讯作者:
Orozco, L.
影响因子:
13.5
作者:
Gong, PF;Cederbaum, AI
通讯作者:
Cederbaum, AI