Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients
Health-related quality of well-being in chronically hospitalized patients with schizophrenia: comparison with matched outpatients
复制标题
DOI：
10.1016/s0165-1781(01)00260-8
复制
发表时间：
2001-08-05
影响因子：
11.3
通讯作者：
Jeste, DV
中科院分区：
文献类型：
--
作者：
Kasckow, JW;Twamley, E;Jeste, DV
量化疾病在生活质量方面的功能后果可以增强我们对精神和身体疾病的理解。然而，很少有人知道老年住院患者与门诊精神分裂症患者的生活质量。我们对54例中老年精神分裂症长期住院患者和一个人口统计学匹配的门诊患者进行了健康相关生活质量评估。使用幸福质量（QWB）量表进行评估，沿着精神病理学和整体认知障碍的标准测量。与门诊患者相比，住院患者的健康相关的生活质量显着较低，作为衡量的QWB。在住院和门诊组中，阳性症状水平较高与健康相关生活质量较低相关。在住院超过6个月的住院患者中，健康相关的生活质量保持相当稳定。在住院患者和门诊患者中，基线认知状态和精神病理学可预测6个月随访时的QWB评分。这些研究结果进一步支持使用QWB在严重的精神疾病人群中，改善老年精神分裂症患者的健康相关的生活质量的影响进行了讨论。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Quantifying (lie functional consequences of illness in terms of quality of life can enhance our understanding of both mental and physical disorders. However, little is known about the quality of life among older inpatients vs. outpatients with schizophrenia. We present the results of health-related quality of life assessments in 54 middle-aged and elderly long-term inpatients with schizophrenia and a demographically matched outpatient sample. Assessments were performed using the Quality of Well-Being (QWB) scale, along with standard measures of psychopathology and global cognitive impairment. Compared with outpatients, the inpatients had a significantly lower health-related quality of life, as measured by the QWB. In the inpatient and outpatient groups, higher levels of positive symptoms were associated with lower health-related quality of life. Health-related quality of life remained fairly stable among the inpatients who remained hospitalized over 6 months. In both inpatients and outpatients, baseline cognitive status and psychopathology predicted QWB scores at the 6-month follow-up. These findings further support the use of the QWB in severely mentally ill populations; implications for improving health-related quality of life among older patients with schizophrenia are discussed. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.