Risk Factors and Timing of Early Stricture Recurrence After Urethroplasty

Risk Factors and Timing of Early Stricture Recurrence After Urethroplasty
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DOI:
10.1016/j.urology.2016.04.033
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发表时间:
2016-09-01
期刊:
影响因子:
2.1
通讯作者:
Gonzalez, Chris M.
Gonzalez, Chris M.
中科院分区:
医学4区
文献类型:
--
作者:
Liu, Joceline S.;Dong, Caroline;Gonzalez, Chris M.

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目的比较尿道成形术后复发情况,确定早期复发的相关危险因素。材料与方法在2001-2010年随访≥ 6个月的262例尿道成形术中,我们确定了65例(24.8%)复发患者(膀胱镜检查修复区域梗阻)。中位随访时间为85.2(6.7-160.1)个月,中位复发时间为8.0(0.5-88.0)个月。最常见的修复术是替代尿道成形术(70.8%),其次是切除和一期吻合术(23.1%)。移植部位以颊部最常见(66.0%),其次为腹壁皮肤(24.5%)。3个月内复发者占21%,6个月内复发者占40.0%,1年内复发者占55.4%,5年以上复发者占9.2%。复发
OBJECTIVE To compare recurrence after urethroplasty, identifying associated risk factors for early recurrence.MATERIALS AND METHODS Among 262 urethroplasties (2001-2010) with >= 6 months of follow-up, we identified 65 patients (24.8%) with recurrence (defined by obstruction in the area of repair on cystoscopy).RESULTS Median stricture length was 4.5 cm (range 1-24 cm). Median follow-up was 85.2 (6.7-160.1) months, with median time to recurrence of 8.0 (0.5-88.0) months. Substitution urethroplasty was the most frequent repair (70.8%), followed by excision and primary anastomosis (23.1%). When graft was used, buccal was most common (66.0%), followed by abdominal wall skin (AWS) (24.5%). Twenty-one percent of recurrences presented within 3 months, 40.0% by 6 months, 55.4% by 1 year, whereas 9.2% recurred more than 5 years later. Recurrences