Personalized medicine: risk prediction, targeted therapies and mobile health technology

Personalized medicine: risk prediction, targeted therapies and mobile health technology
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DOI:
10.1186/1741-7015-12-37
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发表时间:
2014-02-28
期刊:
影响因子:
9.3
通讯作者:
Topol, Eric J.
Topol, Eric J.
中科院分区:
医学1区
文献类型:
--
作者:
Hayes, Daniel F.;Markus, Hugh S.;Topol, Eric J.

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随着与特定疾病相关的基因的发现和靶向治疗的开发,个性化医疗越来越多地应用于临床实践的许多领域。移动应用程序也开始用于医学,旨在提供个性化的疾病管理方法。在某些医学领域,针对患者量身定制的风险预测和治疗已在临床中常规应用,而在其他领域,需要做更多的工作将科学进步转化为个体化治疗。在这篇论坛文章中,我们邀请肿瘤学、神经病学、内分泌学和移动健康技术领域的专家讨论我们在个性化医疗方面的进展,并阐述他们对未来的愿景以及各自领域仍然存在的挑战。
Personalized medicine is increasingly being employed across many areas of clinical practice, as genes associated with specific diseases are discovered and targeted therapies are developed. Mobile apps are also beginning to be used in medicine with the aim of providing a personalized approach to disease management. In some areas of medicine, patient-tailored risk prediction and treatment are applied routinely in the clinic, whereas in other fields, more work is required to translate scientific advances into individualized treatment. In this forum article, we asked specialists in oncology, neurology, endocrinology and mobile health technology to discuss where we are in terms of personalized medicine, and address their visions for the future and the challenges that remain in their respective fields.