Molecular epidemiology of human rotaviruses: Analysis of outbreaks of acute gastroenteritis in Glasgow and the west of Scotland 1981/82 and 1982/83
Molecular epidemiology of human rotaviruses: Analysis of outbreaks of acute gastroenteritis in Glasgow and the west of Scotland 1981/82 and 1982/83
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人类轮状病毒的分子流行病学：格拉斯哥和苏格兰西部1981/82和1982/83急性胃肠炎暴发分析
DOI：
10.1017/s0022172400064238
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发表时间：
1984
影响因子：
--
通讯作者：
Ulrich Desselberger
中科院分区：
文献类型：
--
作者：
E. Follett;R. Sanders;G. Beards;F. Hundley;Ulrich Desselberger
本文采用电子显微镜、酶联免疫吸附试验和RNA迁移模式分析对1981/82年和1982/83年格拉斯哥和苏格兰西部地区轮状病毒感染的分子流行病学进行了研究。1981/82年，“长”型和“短”型（不同变体）轮状病毒从发病开始，在整个暴发的冬季高峰期间共同传播。大约80%的儿童在出生后的第一年受到感染。发病率无性别差异。1982/83年分离出的轮状病毒几乎都是“长”型（有不同的变种），36%的儿童在一岁以后受到感染。血清学上“长”型的轮状病毒为II亚群和血清型，而“短”型的轮状病毒为I亚群和血清型。
SUMMARY The molecular epidemiology of rotavirus infections in Glasgow and the west of Scotland during 1981/82 and 1982/83 was investigated by electron microscopy, ELISA testing and RNA migration pattern analysis. In 1981/82, rotaviruses of both the ‘long’ and the ‘short’ electropherotype (in different variants) co-circulated from the onset throughout the winter peak of the outbreak. Approximately 80 % of the children were infected during the first year of life. No differences in incidence were found between sexes. In 1982/83 the isolated rotaviruses were almost exclusively of the ‘long’ electropherotype (in different variants) and 36% of the children were infected beyond the first year of life. Rotaviruses of the ‘long’ electropherotype serologically were of subgroup II and serotype 1 and those of the ‘short’ electropherotype of subgroup I and serotype 2.