Pattern Formation in Imaginal Disks
Pattern Formation in Imaginal Disks
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想象盘中的图案形成
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
A. Garcı́a
中科院分区：
文献类型：
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作者：
A. Garcı́a
晶体的形状直接由其原子元素的物理性质决定。很可能，病毒的形状仅仅取决于由相应基因编码的不同外壳蛋白的物理化学性质（见Levine， 1969）。相比之下，在多细胞生物中，在受精卵的遗传信息和成体生物的形状之间有几个步骤。在这种情况下，形状出现在细胞增殖、细胞分组和细胞分化之后。因此，任何关于多细胞生物有机形态的因果解释都需要知道遗传信息是如何被处理以构建不同的蛋白质、不同的细胞和不同的细胞排列的。在寻找研究形态发生的实验系统时，人们很快就把注意力转向了形态发生模式。术语形态发生模式目前应用于其中不同类型的元素相对于彼此出现在固定位置的形状。
The shape of a crystal results directly from the physical properties of its atomic elements. Probably, the shape of a virus merely depends on the physico-chemical properties of the different coat proteins, coded by the corresponding genes (see Levine, 1969). By contrast, in multicellular organisms several steps are interposed between the genetic information of the zygote and the shape of the adult organism. In this case, shape appears after cell multiplication, cell grouping and cell differentiation. Thus, any causal explanation of organic shape in multicellular organisms would need to know how the genetic information is processed to build different proteins, different cells and different cell arrangements. When looking for experimental systems to study morphogenesis, attention was soon directed to morpho-genetic patterns. The term morphogenetic pattern is currently applied to shapes in which elements of different types appear located in fixed positions with respect to each other.