A histochemical study of the innervation of cerebral blood vessels in the snake
A histochemical study of the innervation of cerebral blood vessels in the snake
复制标题
蛇脑血管神经支配的组织化学研究
DOI：
10.1007/bf00219792
复制
发表时间：
1977
影响因子：
3.6
通讯作者：
K. Andō
中科院分区：
文献类型：
--
作者：
T. Iijima;T. Wasano;T. Tagawa;K. Andō
用组织化学方法证明蛇脑血管受肾上腺素能纤维和胆碱能纤维的双重支配。虽然神经丛密度稍低，但血管神经支配的基本特征与哺乳动物相似，只是肾上腺素能神经丛比胆碱能神经丛更突出。脑颈动脉系统的主要动脉有丰富的神经供应。然而，神经支配在基底动脉中较不丰富，而在脊（椎）动脉中较少。虽然供应头部右侧的动脉发育不良，但三对动脉，即大脑颈动脉，眼动脉和脊髓，供应蛇脑。颈动脉和眼动脉有密集的神经支配，并伴有粗神经束，表明神经优先沿沿着这些动脉进入颅骨。一些实质小动脉也有双重神经支配。脑实质和脑内毛细血管之间的联系，通过胆碱能和肾上腺素能纤维。此外，还观察到连接毛细血管和髓内神经纤维束的胆碱能神经纤维。毛细血管血流可能受到肾上腺素能和胆碱能中枢神经元的影响。毛细血管壁也表现出强烈的乙酰胆碱酯酶活性。这可能表明毛细血管在脑内血流调节中的重要作用。
Dual innervation of snake cerebral blood vessels by adrenergic and cholinergic fibres was demonstrated with the use of histochemical methods. Although the nerve plexuses are somewhat less dense, the essential features of innervation of the blood vessels are similar to those of mammals with the exception that the adrenergic plexuses are more prominent than the cholinergic plexuses. The major arteries of the cerebral carotid system have a rich nerve supply. However, the innervation is less rich in the basilar and poor in the spinal (vertebral) arteries. Although the arteries supplying the right side of head are poorly developed, three pairs of arteries, cerebral carotids, ophthalmics and spinals, supply the snake brain. The carotids and ophthalmics are densely innervated and are accompanied by thick nerve bundles, suggesting that the nerves preferentially enter the skull along those arteries. Some parenchymal arterioles are also dually innervated. Connection between the brain parenchyma and intracerebral capillaries via both cholinergic and adrenergic fibres was observed. In addition cholinergic nerve fibres, connecting capillaries and the intramedullary nerve fibre bundles, were noticed. Capillary blood flow may be influenced by both adrenergic and cholinergic central neurons. The walls of capillaries also exhibit heavy acetylcholinesterase activity. This may indicate an important role for the capillary in the regulation of intracerebral blood flow.