TREATMENT OF SEVERE INTRAVENTRICULAR HEMORRHAGE BY INTRAVENTRICULAR INFUSION OF UROKINASE
TREATMENT OF SEVERE INTRAVENTRICULAR HEMORRHAGE BY INTRAVENTRICULAR INFUSION OF UROKINASE
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DOI：
10.1007/bf00417665
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发表时间：
1995-01-01
影响因子：
2.8
通讯作者：
KAVUNCU, I
中科院分区：
文献类型：
--
作者：
AKDEMIR, H;SELCUKLU, A;KAVUNCU, I
在过去的三年中，七个严重的脑室出血病人收住我们的诊所，直接脑室内注入尿激酶治疗。出血均扩散至整个脑室腔，并有管型形成，第三、四脑室扩大，平均第三、四脑室在出血后第三天开始清晰，侧脑室在出血后第九天开始清晰。7例患者中有5例恢复良好或仅中度残疾，2例死亡。治疗期间未发生尿激酶副作用引起的感染、惊厥、再出血和外周或继发性出血。我们的结论是，该手术可以有效和安全地应用于严重脑室出血。
During the last three years, seven patients with severe intraventricular hemorrhage admitted to our clinic were treated with direct intraventricular infusion of urokinase. In each case, hemorrhage extended into the entire ventricular cavity and cast formation as well as an expansion of third and fourth ventricles were found. On the average, both the third and fourth ventricles became clear on the third day and the lateral ventricle on the ninth day after hemorrhage. Five of the seven patients showed good recovery or only moderate disability, and two died. Infection, convulsion, rebleeding, and peripheral or secondary hemorrhage due to the side effects of urokinase was not encountered during therapy. We conclude that this procedure can be applied effectively and safely in severe intraventricular hemorrhage.