Building a network for multicenter, prospective research of central nervous system infections in South America: Process and lessons learned.
Building a network for multicenter, prospective research of central nervous system infections in South America: Process and lessons learned.
复制标题
建立南美洲中枢神经系统感染多中心前瞻性研究网络：过程和经验教训。
DOI：
10.1016/j.ensci.2018.07.001
复制
发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Rome
中科院分区：
文献类型：
--
作者：
Nelson,Christina;Mori,Nicanor;Ton,Thanh;Zunt,Joseph;MeningoencephalitisWorkingGroup;Kochel,T;Romero,A;Gadea,N;Tilley,D;Ticona,E;Soria,J;Celis,V;Huanca,D;Delgado,A;Rivas,M;Stiglich,M;Sihuincha,M;Donayre,G;Celis,J;Rome
多中心协作网络对于推进各种条件下的研究和改善临床护理至关重要。研究网络对于中枢神经系统感染尤其重要，由于其零星发生和需要收集和检测脑脊液，对其研究仍然很困难。在资源有限的地区建立长期研究网络还有助于诊断能力建设、监测新出现的病原体，并在需要时提供适当的治疗。我们回顾了自2009年以来在秘鲁五个城市的12家医院之间建立脑炎研究网络的经验。我们提供了切实可行的建议，以帮助其他对推进资源有限地区中枢神经系统感染研究感兴趣的团体。
Multicenter collaborative networks are essential for advancing research and improving clinical care for a variety of conditions. Research networks are particularly important for central nervous system infections, which remain difficult to study due to their sporadic occurrence and requirement for collection and testing of cerebrospinal fluid. Establishment of long-term research networks in resource-limited areas also facilitates diagnostic capacity building, surveillance for emerging pathogens, and provision of appropriate treatment where needed. We review our experience developing a research network for encephalitis among twelve hospitals in five Peruvian cities since 2009. We provide practical suggestions to aid other groups interested in advancing research on central nervous system infections in resource-limited areas.