Nonadherence Consensus Conference Summary Report
Nonadherence Consensus Conference Summary Report
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DOI：
10.1111/j.1600-6143.2008.02495.x
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发表时间：
2009-01-01
影响因子：
8.8
通讯作者：
Dobbels, F.
中科院分区：
文献类型：
--
作者：
Fine, R. N.;Becker, Y.;Dobbels, F.
本报告是关于免疫抑制剂不依从性（NA）的“共识会议”的总结。其目标是：（1）讨论NA的定义、患病率和测量方法、其危险因素以及对临床和经济结局和干预措施的影响;（2）为未来的研究提供建议。2008年1月，在佛罗里达举行了一次为期两天的会议，邀请了66名医疗和联合健康坚持移植和非移植专家。一个科学委员会筹备了这次会议。通过全体会议和互动式发言以及小组讨论达成了共识。全体会议发言人事先准备了一份摘要。分组领导人在会议之前通过电话会议和电子邮件在小组成员之间发起讨论，并在会后提供摘要。结论是NA：（a）比我们假设的更普遍;（B）难以准确测量;（c）倾向于产生更差的结果;（d）由于许多原因和系统相关因素（包括患者的文化、医疗保健提供者和环境）而发生;以及（e）目前尚不知道如何提高依从性。这份共识报告为今后就这一复杂、多方面的问题开展研究提供了一些路线图。
This report is a summary of a 'Consensus Conference' on nonadherence (NA) to immunosuppressants. Its aims were: (1) to discuss the state-of-the-art on the definition, prevalence and measurement of NA, its risk factors and impact on clinical and economical outcomes and interventions and (2) to provide recommendations for future studies. A two-day meeting was held in Florida in January 2008, inviting 66 medical and allied health adherence transplant and nontransplant experts. A scientific committee prepared the meeting. Consensus was reached using plenary and interactive presentations and discussions in small break-out groups. Plenary presenters prepared a summary beforehand. Break-out group leaders initiated discussion between the group members prior to the meeting using conference calls and e-mail and provided a summary afterward. Conclusions were that NA: (a) is more prevalent than we assume; (b) is hard to measure accurately; (c) tends to confer worse outcomes; (d) happens for a number of reasons, and system-related factors including the patient's culture, the healthcare provider and the setting and (e) it is not currently known how to improve adherence. This consensus report provided some roadmaps for future studies on this complicated, multifaceted problem.