A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells.
A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells.
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DOI：
10.1039/c5cc02452h
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发表时间：
2015-05
影响因子：
4.9
通讯作者：
Wei Wang;Chen Chen-Chen;Xiaoxiao Li;Shiying Wang;Xiliang Luo
中科院分区：
文献类型：
--
作者：
Wei Wang;Chen Chen-Chen;Xiaoxiao Li;Shiying Wang;Xiliang Luo
基于正电荷修饰的Au纳米笼和适配体分子门，建立了一种高灵敏度、高选择性检测细胞内ATP的新型控释生物检测方法，并成功应用于活细胞内ATP的荧光显微成像。
A novel controlled-release bioassay for highly sensitive and selective detection of intracellular ATP was developed based on positive charge-modified Au nanocages capped with an aptamer molecular gate, and it was used successfully for fluorescence microscopy imaging of ATP in living cells.