VALIDITY OF FAMILY HISTORY DATA ON SEVERE HEADACHE AND MIGRAINE
VALIDITY OF FAMILY HISTORY DATA ON SEVERE HEADACHE AND MIGRAINE
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DOI：
10.1212/wnl.43.10.1954
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发表时间：
1993-10-01
期刊：
影响因子：
9.9
通讯作者：
LIPTON, RB
中科院分区：
文献类型：
--
作者：
OTTMAN, R;HONG, S;LIPTON, RB
本研究在一项癫痫性疾病的家庭研究中评估了从成年癫痫先证者中获得的严重头痛和偏头痛家族史数据的有效性。我们将先证者报告的父母和同父异母兄弟姐妹的严重头痛和偏头痛与基于自我报告的症状诊断进行了比较。严重头痛和偏头痛的总体敏感性分别为48%和44%。当我们使用严重头痛的报告来筛选亲属的偏头痛时，敏感性为56%。这些结果表明严重头痛和偏头痛在家族史访谈中被低估与一级亲属。为了获得临床实践和基因研究中家庭头痛的准确信息，可能需要与每个亲属直接面谈。
This study evaluated the validity of family history data on severe headache and migraine obtained from adult probands with epilepsy in a family study of seizure disorders. We compared the probands' reports of severe headaches and migraines in their parents and full siblings with symptom-based diagnoses based on self-reports. Overall sensitivity was 48% for severe headache and 44% for migraine. When we used reports of severe headaches to screen for migraine headaches in the relatives, sensitivity was 56%. These results indicate that severe headache and migraine are underreported in family history interviews with first-degree relatives. To obtain accurate information on headaches in families for clinical practice and genetic research, direct interviews with each relative may be required.