Curved ratchets improve bacteria rectification in microfluidic devices.

Curved ratchets improve bacteria rectification in microfluidic devices.
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弯曲棘轮可改善微流体装置中的细菌矫正。

DOI:
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发表时间:
2021
期刊:
影响因子:
2.4
通讯作者:
V. Kantsler
V. Kantsler
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Simone Coppola;V. Kantsler

文献摘要

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我们研究了如何在微流体设备中的细菌整流可以通过使用不同形状和大小的八个棘轮进行实验来优化。结果表明,弯曲的棘轮性能最好,并且它们的曲率半径影响它们的性能,因为它影响细菌在棘轮表面上停留的时间。我们发现最佳的细菌棘齿是半径为60μm,凹部为15μm的棘齿。我们还表明,细菌离开棘轮的角度可以在其效率中发挥重要作用。最后,我们在一个简单的数值模拟中重现了我们的实验条件,以证实我们的发现。
We study how bacteria rectification in microfluidics devices can be optimized by performing experiments with eight ratchets of different shape and size. Results show that curved ratchets perform best and that their radius of curvature influences how well they perform, as it affects the time bacteria spend on the ratchet surface. We find that the optimal bacterial ratchet is a 60μm radius semicircle witch 15μm concavities. We also show that the angle at which bacteria leave the ratchets can play an important role in their efficiency. Lastly, we reproduce our experimental conditions in a simple numerical simulation to confirm our findings.