Efficacy study of intensive cis‐platin therapy in advanced non‐small cell bronchogenic carcinoma
Efficacy study of intensive cis‐platin therapy in advanced non‐small cell bronchogenic carcinoma
复制标题
顺铂强化治疗晚期非小细胞支气管癌的疗效研究
作者：
S. Vogl;M. Berenzweig;F. Camacho;E. Greenwald;B. Kaplan
30例晚期非小细胞支气管癌患者接受顺式铂治疗，每周75 mg/M2，持续3周，然后每3周治疗一次。其中18例为门诊，22例为远处转移，14例有放疗史，无化疗史。10例患者（33%）的客观缓解持续时间中位数为3个月。应答者的中位寿命为5个月，而无应答者的中位寿命为3个月。12例患者出现短暂性轻度氮血症。顺式铂在非小细胞支气管源性癌中有明确但适度的活性。
Thirty patients with advanced non‐small cell bronchogenic carcinoma were treated with cis‐platin, 75 mg/M2 weekly for three weeks, then every three weeks. Eighteen were ambulatory, 22 had distant metastases, 14 had prior irradiation, and none had prior chemotherapy. Ten patients (33%) had objective remissions lasting a median of three months. Responders lived a median of five months, compared to three months for nonresponders. Transient mild azotemia was noted in twelve patients. Cis‐platin has definite but modest activity in non‐small cell bronchogenic carcinoma.
使用博莱霉素、阿霉素、甲氨蝶呤和顺式二氯二氨铂 (II) (BAMP) 联合化疗治疗非小细胞支气管癌。
DOI：
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发表时间：
1980
期刊：
Cancer treatment reports
影响因子：
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作者：
Vogl,SE;Wollner,D;Kaplan,BH;Berenzweig,M
通讯作者：
Berenzweig,M