Respiratory Syncytial Virus-Associated Hospitalizations Among Children Less Than 24 Months of Age
Respiratory Syncytial Virus-Associated Hospitalizations Among Children Less Than 24 Months of Age
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DOI：
10.1542/peds.2013-0303
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发表时间：
2013-08-01
期刊：
影响因子：
8
通讯作者：
Iwane, Marika K.
中科院分区：
文献类型：
--
作者：
Breese, Caroline;Weinberg, Geoffrey A.;Iwane, Marika K.
背景：呼吸道合胞病毒（RSV）感染是婴儿住院的主要原因。然而，RSV住院负担的估计值各不相同，精确度受到6至>= 12个月的年龄分层的限制。方法：我们分析了一项为期5年的前瞻性研究，对因实验室确诊的（逆转录聚合酶链反应）RSV急性呼吸道疾病（ARI）在2000年10月至2005年3月。总人口的风险分层按月的年龄由出生证明信息，以产生住院率rate.RESULTS：有559（26%）RSV感染的儿童在2149名儿童住院ARI（85%的所有符合条件的儿童ARI）。平均RSV住院率为每1000名儿童5.2例
BACKGROUND: Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization among infants. However, estimates of the RSV hospitalization burden have varied, and precision has been limited by the use of age strata grouped in blocks of 6 to >= 12 months.METHODS: We analyzed data from a 5-year, prospective, population-based surveillance for young children who were hospitalized with laboratory-confirmed (reverse-transcriptase polymerase chain reaction) RSV acute respiratory illness (ARI) during October through March 2000-2005. The total population at risk was stratified by month of age by birth certificate information to yield hospitalization rates.RESULTS: There were 559 (26%) RSV-infected children among the 2149 enrolled children hospitalized with ARI (85% of all eligible children with ARI). The average RSV hospitalization rate was 5.2 per 1000 children