[Squamous epithelial carcinoma at the site of lichen ruber hypertrophicus of the glans penis].
[Squamous epithelial carcinoma at the site of lichen ruber hypertrophicus of the glans penis].
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阴茎头肥大性红苔藓部位鳞状上皮癌[J].
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
H. Hamm
中科院分区：
文献类型：
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作者：
J. Wörheide;G. Bonsmann;G. Kolde;H. Hamm
关于扁平苔藓癌变的报道大多数涉及口腔糜烂型。报告的恶性转化频率范围在1%至10%之间。有一些孤立的观察恶性转化的皮肤扁平苔藓。在这些病例中，位于下肢的肥大型占优势。我们报告一个不寻常的情况下，鳞状细胞癌发展的阴茎头在存在肥厚性扁平苔藓。用氨苯砜、类维生素A、皮质类固醇和局部环孢菌素A对扁平苔藓进行系统治疗未能阻止这种发展。
Reports of cancer development in lichen planus mostly concern the oral erosive form. The reported frequency of malignant transformation ranges between less than 1% and 10%. There have been a few isolated observations of malignant transformation of cutaneous lichen planus. In these cases, the hypertrophic type located on the lower limbs predominated. We report an unusual case of squamous cell carcinoma developing on the glans penis in the presence of hypertrophic lichen planus. Systemic treatment of the lichen planus with dapsone, retinoids, corticosteroids and topical cyclosporin A failed to prevent this development.