Assessing quality of life in older adults with cognitive impairment
Assessing quality of life in older adults with cognitive impairment
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DOI：
10.1097/00006842-200205000-00016
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发表时间：
2002-05-01
影响因子：
3.3
通讯作者：
Teri, L
中科院分区：
文献类型：
--
作者：
Logsdon, RG;Gibbons, LE;Teri, L
目的：本文讨论了理论，心理测量学，和实际考虑的生活质量评估老年人认知障碍。它描述了一种新的衡量痴呆症生活质量的方法，QOL-AD，并检查了患者和护理人员报告患者生活质量的可靠性和有效性。方法：受试者为177例患者/照顾者二人组。患者简易精神状态检查评分范围为0 - 29，平均评分为16（SD = 7）。每位患者和护理人员根据QOL-AD对患者的生活质量进行评分。患者的功能和认知状态，心理状态，身体功能和行为问题也进行了评估。在三个认知障碍水平上检查了患者QOL-AD报告的可靠性和有效性。结果：155例患者均能完成QOL-AD。完成者在简易精神状态检查中的得分在4到29之间，而未完成者的得分都在10或更低。患者和护理人员QOL-AD报告的可靠性良好（a值范围为0.83至0.90）。患者和护理人员报告在认知水平上的有效性得到了抑郁（r = -0.41至-0.65），日常功能（r = -0.10至-0.43）和愉快事件频率（r = 0.18至0.51）测量值的相关性的支持。在所有认知水平中，患者和护理人员报告之间的组内相关性均为正相关（r = 0.14至0.39）。结论：QOL-AD对MMSE评分大于10分的个体是可靠和有效的。需要进一步的研究，以澄清患者和照顾者之间的关系，患者的生活质量的报告，并确定影响生活质量的因素，在整个痴呆症的进展。
Objective: This article discusses theoretical, psychometric, and practical considerations of quality of life assessment in older adults with cognitive impairment. It describes a new measure of quality of life in dementia, the QOL-AD, and examines the reliability and validity of patient and caregiver reports of patient quality of life. Methods: Subjects were 177 patient/caregiver dyads. Patient Mini Mental State Exam scores ranged from 0 to 29, with a mean score of 16 (SD = 7). Each patient and caregiver rated the patient's quality of life on the QOL-AD. Patient functional and cognitive status, psychological state, physical function, and behavior problems were also assessed. Reliability and validity of patient QOL-AD reports were examined across three levels of cognitive impairment. Results: One hundred, fifty-five patients were able to complete the QOL-AD. Completers scored between 4 and 29 on the Mini Mental State Exam, whereas noncompleters all scored 10 or lower. Reliability for both patient and caregiver reports on the QOL-AD was good (a values ranged from 0,83 to 0.90). Validity of patient and caregiver reports across cognitive levels was supported by correlation with measures of depression (r = -0.41 to -0.65), day-to-day functioning (r = -0.10 to -0.43), and pleasant events frequency (r = 0.18 to 0.51). Intraclass correlation between patient and caregiver reports was positive across all cognitive levels (r = 0.14 to 0.39). Conclusions: The QOL-AD seems to be reliable and valid for individuals with MMSE scores greater than 10. Further research is needed to clarify the relationship between patient and caregiver reports of patient quality of life and to identify factors that influence quality of life throughout the progression of dementia.