Update on the incidence and mortality from melanoma in the United States
Update on the incidence and mortality from melanoma in the United States
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DOI：
10.1016/s0190-9622(99)70562-1
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发表时间：
1999-01-01
影响因子：
13.8
通讯作者：
Bewerse, B
中科院分区：
文献类型：
--
作者：
Hall, HI;Miller, DR;Bewerse, B
背景：在美国，恶性黑色素瘤发病率的增长在所有癌症中是幅度较大的。
目的：我们报告美国白人人群中黑色素瘤发病率的最新趋势。
方法：计算1973年至1994年的发病率和死亡率。按州、年龄、性别以及解剖部位、分期和诊断时黑色素瘤的厚度进行分层分析趋势。
结果：从1973年到1994年，黑色素瘤的发病率和死亡率大幅上升，分别增长了120.5%和38.9%。然而，近年来，大多数年龄 - 性别组的发病率似乎趋于稳定甚至下降。男性患者的发病率和死亡率持续高于女性患者，但无论男女，按部位来看增长幅度最大的是躯干部位。大部分黑色素瘤在局部阶段被发现，且厚度小于0.75毫米。
结论：建议预防阳光照射以扭转黑色素瘤的高发病率。
Background: Increases in the incidence of malignant melanoma have been among the largest of all cancers in the United States.Objective: We report updated trends in melanoma rates among the US white population.Methods: Incidence and mortality rates were calculated for 1973 to 1994. Trends were examined with stratification by state, age, and sex, and by anatomic site, stage, and melanoma thickness at diagnosis.Results: Melanoma incidence and mortality rates increased dramatically from 1973 to 1994, rising 120.5% and 38.9%, respectively. In recent years, however, rates for most age-sex groups appeared to stabilize or even decline. Male patients continued to have higher incidence and mortality rates than female patients, but for both male and female patients the largest increases by site were for the trunk. A large proportion of melanomas were detected in the local stage and with a thickness less than 0.75 mm.Conclusion: Prevention of sun exposure is recommended to reverse the high incidence rates of melanoma.