KAWASAKI-DISEASE IN INFANTS LESS-THAN ONE-YEAR OF AGE
KAWASAKI-DISEASE IN INFANTS LESS-THAN ONE-YEAR OF AGE
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DOI：
10.1016/s0022-3476(95)70344-6
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发表时间：
1995-04-01
影响因子：
5.1
通讯作者：
SHULMAN, ST
中科院分区：
文献类型：
--
作者：
ROSENFELD, EA;CORYDON, KE;SHULMAN, ST
目的：为了确定严重后遗症的危险因素，分析疾病特征，并评估静脉注射免疫球蛋白（IVGG）治疗小于12个月的川崎病患儿的疗效。设计：回顾性分析1980年至1993年间小于12个月的川崎病患儿的病历资料。在443例川崎患者中，57例（13%）小于1岁，其中14例（3%）小于6个月。发病年龄是冠状动脉瘤（CAA）和巨大（>8 mm）动脉瘤发生的预测因素：14名儿童中有11名（79%）
Objective: To identify risk factors for severe sequelae, analyze disease characteristics, and assess efficacy of intravenously administered immune globulin (IVGG) therapy in infants less than 12 months of age with Kawasaki disease.Design: Retrospective chart review of children less than 12 months of age with Kawasaki disease between 1980 and 1993.Results: Of 443 patients with Kawasaki disease, 57 (13%) were less than 1 year of age, including 14 (3%) less than 6 months. Age at onset was a predictor of the development of coronary artery aneurysms (CAA) and of giant (>8 mm) aneurysms: 11 (79%) of 14 children