Impact of the COVID-19 pandemic on the diagnosis of cancer in Japan: analysis of hospital-based cancer registries
Impact of the COVID-19 pandemic on the diagnosis of cancer in Japan: analysis of hospital-based cancer registries
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DOI：
10.1093/jjco/hyac129
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发表时间：
2022-07-31
影响因子：
2.4
通讯作者：
Higashi, Takahiro
中科院分区：
文献类型：
--
作者：
Okuyama, Ayako;Watabe, Mari;Higashi, Takahiro
自日本政府于4月在COVID-19疫情期间首次宣布进入紧急状态以来，确诊为癌症并开始接受治疗的患者人数有所减少。背景由于冠状病毒病大流行，癌症护理受到了严重影响，这一点令人担忧。利用国家数据库，我们记录了大流行对日本癌症诊断的影响。方法对735家医院癌症登记处的数据进行分析，覆盖了>70%的新诊断病例。我们比较了2016-2019年和2020年的癌症类型，诊断过程，阶段和13个都道府县的趋势，这些都道府县需要采取特别预防措施以防止感染传播。总体而言，2020年开始治疗的患者人数与2016-2019年的平均人数相比下降了1. 9%。胃部病例急剧下降13.8%。病例下降（所有癌症下降22.0%）在5月份更为明显。2020年，癌症筛查和由此导致的检测率显著下降（8. 1 - 24. 3%）。I、II期胃癌、II期肝内胆管癌、II期食管癌、0、I期喉癌、II期胆囊癌的病例登记数较2018年、2019年下降均在10%以上。按居住地区划分的癌症病例趋势显示，与其他地区相比，2020年5月13个都道府县的癌症病例有所下降。结论在2020年冠状病毒大流行期间，癌症诊断数量有所下降，特别是在日本政府于4月宣布第一次紧急状态之后。我们需要仔细观察这些诊断率下降或护理延迟对患者生存率或人群死亡率的影响。
The number of patients diagnosed with cancer who initiated treatment reduced since the Japanese government first declared the state of emergency in April during the COVID-19 pandemic.Background There is significant concern that cancer care is adversely impacted due to the coronavirus disease pandemic. Using the national database, we document the impact of the pandemic on cancer diagnosis in Japan. Methods Data from 735 hospital-based cancer registries, covering >70% of newly diagnosed cases, were analysed. We compared trends during 2016-2019 and those in 2020 by the type of cancer, diagnostic process, stage and 13 prefectures as requiring special precautions to prevent the spread of infection. Results Overall, the number of patients who began treatment decreased by 1.9% in 2020 as compared with the average number during 2016-2019. A sharp decline of 13.8% was observed for stomach cases. The decline in cases (22.0% decrease for all cancers) was more pronounced in May. Cancer screening and resulting detection decreased significantly in 2020 (8.1-24.3%). Case registrations of stage I and II gastric cancer, stage II intrahepatic cholangiocarcinoma, stage II oesophageal cancer, stage 0 and I laryngeal cancer and stage II gallbladder cancer decreased by >10% compared with those in 2018 and 2019. The trends in cancer cases by area of residence indicated a decline in 13 prefectures in May 2020 compared with other areas. Conclusions The number of cancer diagnoses decreased during the year 2020 under coronavirus pandemic, especially right after the Japanese government declared the first state of emergency in April. We need to carefully observe the consequences of these decrease in diagnosis, or perhaps the delay in care, on patient survival or population mortality.