Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study
Autism Spectrum Disorder Reclassified: A Second Look at the 1980s Utah/UCLA Autism Epidemiologic Study
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DOI：
10.1007/s10803-012-1566-0
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发表时间：
2013-01-01
影响因子：
3.9
通讯作者：
McMahon, William M.
中科院分区：
文献类型：
--
作者：
Miller, Judith S.;Bilder, Deborah;McMahon, William M.
本研究的目的是重新审视20世纪80年代进行的一项全州自闭症患病率研究（n = 489）中的诊断数据，以研究更广泛的诊断标准对自闭症谱系障碍（ASD）病例状况的影响。在最初的108名“诊断为非自闭症”的个体中，有64人（59%）符合当前的ASD病例定义。新确定的群体的平均智商估计值（智商 = 35.58；标准差 = 23.01）显著低于原始群体（智商 = 56.19，标准差 = 21.21；t = 5.75；p <.0001）。将如今的诊断标准应用于20世纪80年代确定的参与者，发现了更多伴有智力残疾的自闭症病例。当前的分析将这项历史性工作置于背景之中，并强调了几十年前进行的流行病学研究与当今研究在确定病例方面的差异。
The purpose of the present study was to re-examine diagnostic data from a state-wide autism prevalence study (n = 489) conducted in the 1980s to investigate the impact of broader diagnostic criteria on autism spectrum disorder (ASD) case status. Sixty-four (59 %) of the 108 originally "Diagnosed Not Autistic" met the current ASD case definition. The average IQ estimate in the newly identified group (IQ = 35.58; SD = 23.01) was significantly lower than in the original group (IQ = 56.19 SD = 21.21; t = 5.75; p < .0001). Today's diagnostic criteria applied to participants ascertained in the 1980s identified more cases of autism with intellectual disability. The current analysis puts this historic work into context and highlights differences in ascertainment between epidemiological studies performed decades ago and those of today.