The Relationship Between Serum Calcium Level, Blood Lipids, and Blood Pressure in Hypertensive and Normotensive Subjects who Come from a Normal University in East of China
The Relationship Between Serum Calcium Level, Blood Lipids, and Blood Pressure in Hypertensive and Normotensive Subjects who Come from a Normal University in East of China
复制标题
华东师范大学高血压及正常血压受试者血清钙水平、血脂、血压的关系
DOI：
10.1007/s12011-013-9646-3
复制
发表时间：
2013-06-01
影响因子：
3.9
通讯作者：
Yu, Jiegen
中科院分区：
文献类型：
--
作者：
Yao, Yingshui;He, Lianping;Yu, Jiegen
此前的研究表明，钙摄入量低与高血压等心血管疾病的高患病率有关。然而，血清钙与血压之间的关系尚不清楚。我国高血压患病率较高。因此，本研究的目的是评估高血压组和正常血压组之间的血清钙水平，并探讨血清钙、血压和血脂参数之间的相关性。共有 1,135 名成年受试者参与了这项研究，并被分为两个研究组：收缩压 (SBP) 140 mmHg 或更高或舒张压 (DBP) 90 mmHg 或更高的高血压组 (n= 316) 和年龄和性别匹配的正常血压组 (n= 819、120 mmHg 或更低) SBP 和 80 mmHg 或更低的 DBP）。我们的结果表明，男性（60 岁或以上）存在随着血清钙水平升高而血压降低的显着趋势，但女性没有发现这种趋势。血压正常组中，舒张压与总胆固醇（P<0.01）、甘油三酯（P<0.01）呈显着正相关，甘油三酯与收缩压也呈显着正相关（P<0.01）。总体而言，这些数据表明血清钙可能对患有高血压的老年男性受试者的血压和血压正常受试者的血脂谱有影响。
Previous studies revealed that low calcium intake is related to high prevalence of cardiovascular diseases such as hypertension. However, the relationship between serum calcium and blood pressure was unclear. The prevalence of hypertension is high in China. Thus, the aim of this study was to evaluate the serum calcium level between hypertensive and normotensive groups and to investigate the correlation between serum calcium, blood pressure, and blood lipid parameters. A total of 1,135 adult subjects participated in this study and were divide into two study groups: a hypertensive group (n= 316) who had 140 mmHg or higher in systolic blood pressure (SBP) or 90 mmHg or higher in diastolic blood pressure (DBP) and an age- and sex-matched normotensive group (n= 819, 120 mmHg or less SBP and 80 mmHg or less DBP). Our results indicate a significant trend for men (60 years old or older) in the direction of decreasing blood pressure with increasing serum calcium level, but no trend for women was indicated. In the normotensive group, a significant positive correlation was found between DBP and total cholesterol (P< 0.01) and triglyceride (P< 0.01), Likewise, triglyceride was positively correlated with SBP (P< 0.01). Overall, these data suggest that serum calcium may have an influence in the blood pressure of older male subjects with hypertension and in blood lipid profiles of normotensive subjects.