Termite sociogenomics: evolution and regulation of caste-specific expressed genes
Termite sociogenomics: evolution and regulation of caste-specific expressed genes
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DOI：
10.1016/j.cois.2022.100880
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发表时间：
2022-02-14
影响因子：
5.3
通讯作者：
Lo, Nathan
中科院分区：
文献类型：
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作者：
Maekawa, Kiyoto;Hayashi, Yoshinobu;Lo, Nathan
白蚁基因组已在来自四个不同科的至少五个物种中进行了测序。基于基因组的转录组分析已经鉴定出大量具有种姓特异性表达模式的蛋白质编码基因。这些基因包括那些涉及种姓特异性形态和作用的基因，例如繁殖力高和寿命长。一些种姓特异性表达基因属于多基因家族，它们的遗传结构和表达谱表明它们是通过串联基因复制进化的。种姓特异性表达的候选调控机制包括表观遗传调控（例如组蛋白修饰和非编码RNA）以及转录因子和顺式调控元件的多样化。我们回顾了白蚁社会基因组学领域的现有知识，重点关注种姓特异性表达基因的进化和调控，并讨论了未来的研究方向。
Termite genomes have been sequenced in at least five species from four different families. Genome-based transcriptome analyses have identified large numbers of protein-coding genes with caste-specific expression patterns. These genes include those involved in caste-specific morphologies and roles, for example high fecundity and longevity in reproductives. Some caste-specific expressed genes belong to multi-gene families, and their genetic architecture and expression profiles indicate they have evolved via tandem gene duplication. Candidate regulatory mechanisms of castespecific expression include epigenetic regulation (e.g. histone modification and non-coding RNA) and diversification of transcription factors and cis-regulatory elements. We review current knowledge in the area of termite sociogenomics, focussing on the evolution and regulation of caste-specific expressed genes, and discuss future research directions.