DISTRIBUTION OF CALRETININ, CALBINDIN-D28K, AND PARVALBUMIN IN THE RAT THALAMUS
DISTRIBUTION OF CALRETININ, CALBINDIN-D28K, AND PARVALBUMIN IN THE RAT THALAMUS
复制标题
DOI：
10.1016/0361-9230(94)90086-8
复制
发表时间：
1994-01-01
影响因子：
3.8
通讯作者：
DEURA, S
中科院分区：
文献类型：
--
作者：
ARAI, R;JACOBOWITZ, DM;DEURA, S
对大鼠丘脑中三种钙结合蛋白（钙结合蛋白、钙结合蛋白-D28k 和小白蛋白）的定位进行了免疫组织化学检查。 a) 一些丘脑区域显示细胞几乎只含有一种钙结合蛋白。例如，在中央内侧核和室旁核中几乎只发现钙结合蛋白染色的细胞。 Calbindin-D28k 染色的细胞主要发现于中央外侧、前内侧、前内侧和后核。在网状核的中央部分仅发现小白蛋白阳性细胞。 b) 其他区域表示由不同钙结合蛋白组成的两种细胞成分的分布之间的重叠。例如，在后核、中背核、菱形核和 reuniens 核中都发现了钙结合蛋白染色的细胞和钙结合蛋白-D28k 标记的细胞。 c) 其他区域显示没有细胞被任何钙结合蛋白染色。例如，通常在前背核、前腹核、腹外侧核、腹后外侧核、腹后内侧核、或胶状肌核、或中背核中央部分的神经元中检测不到钙结合蛋白。这三种蛋白质可作为定位丘脑内神经元亚群的有用标记。
The localization of three calcium-binding proteins, calretinin, calbindin-D28k, and parvalbumin, in the rat thalamus was immunohistochemically examined. a) Some thalamic regions revealed cells almost exclusively containing one of the calcium-binding proteins. For example, almost only calretinin-stained cells were found in the central medial and paraventricular nuclei. Calbindin-D28k-stained cells were mostly found in the centrolateral, interanteromedial, anteromedial, and posterior nuclei. Only parvalbumin-positive cells were found in the central part of the reticular nucleus. b) Other regions expressed overlap between the distributions of two cell components composed of different calcium-binding proteins. For example, both calretinin-stained cells and calbindin-D28k-labeled cells were found in the lateroposterior, intermediodorsal, rhomboid, and reuniens nuclei. c) Other regions showed no cells stained for any of the calcium-binding proteins. For example, generally no calcium-binding protein was detected in neurons of the anterodorsal, anteroventral, ventrolateral, ventral posterolateral, ventral posteromedial, or gelatinosus nuclei, or of the central part of the mediodorsal nucleus. These three proteins serve as useful marker for localizing subpopulations of neurons within the thalamus.