Apatite coating on hydrophilic polymer-grafted poly(ethylene) films using an alternate soaking process
Apatite coating on hydrophilic polymer-grafted poly(ethylene) films using an alternate soaking process
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DOI：
10.1016/s0142-9612(00)00162-9
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发表时间：
2001-01-01
期刊：
影响因子：
14
通讯作者：
Akashi, M
中科院分区：
文献类型：
--
作者：
Taguchi, T;Muraoka, Y;Akashi, M
在此之前，我们开发了一种新的交替浸泡工艺，并阐明了使用该工艺在有机聚合物水凝胶基质上/在有机聚合物水凝胶基质中形成了类骨磷灰石。本文研究了不同接枝密度的亲水聚合物接枝聚乙烯(PE)膜上的磷灰石涂层，并采用了常用的亲水性聚合物聚丙烯酰胺(PAAM)和聚丙烯酸(PAAc)。X-射线衍射分析表明，在PAAm或PAAc接枝的PE膜上包覆了羟基磷灰石。PAAM接枝PE(PAAM-g-PE)膜的磷灰石包覆量随反应周期的增加和PAAM接枝密度的增加而增加。与PAAm-g-PE相似，PAAc-g-PE(PAAc-g-PE)膜上的磷灰石包覆量随着PAAc接枝密度的增加而线性增加，最高可达30µg/cm(2)。而当PAAc的接枝密度超过30mug/cm(2)时，即使经过50个反应循环，PAAc-g-PE膜上的磷灰石涂层也没有明显增加。在原始PE膜上没有观察到磷灰石涂层。扫描电子显微镜显示，接枝密度为10~30mug/cm(2)的PAAm-g-PE膜和PAAc-g-PE膜上均有磷灰石晶体的聚集。另一方面，当PAAc链的接枝密度大于30mug/cm(2)时，磷灰石层致密，且有一定的裂隙。这些结果表明，可以通过交替浸渍工艺在亲水聚合物接枝PE膜上包覆磷灰石，并且磷灰石的结晶形态可以作为聚合物类型和密度的函数来控制。(C)2000爱思唯尔科学有限公司。保留所有权利。
Previously, we developed a novel alternate soaking process and clarified that bone-like apatite was formed on/in organic polymer hydrogel matrices using this process. The present study focused on the apatite coating on hydrophilic polymer grafted poly(ethylene) (PE) films with various grafting densities and commonly used hydrophilic polymers, poly(acryl amide) (PAAm) and poly(acrylic acid) (PAAc) were employed. From X-ray diffraction analysis, hydroxyapatite was coated on PAAm- or PAAc- grafted PE films. The amount of apatite coated on PAAm-grafted PE (PAAm-g-PE) films increased with an increase in the reaction cycles and the grafting density of PAAm. Similar to PAAm-g-PE, the amount of apatite coated on PAAc-grafted PE (PAAc-g-PE) films increased linearly with an increase in the grafting density of the PAAc up to around 30 mug/cm(2). While, no significant increase in the apatite coating on the PAAc-g-PE films was observed even after 50 reaction cycles when the grafting densities of PAAc were over 30 mug/cm(2). Apatite coating was not observed on original PE films. Scanning electron microscopic images reveal that the aggregation of apatite crystals on all PAAm-g-PE films and PAAc-g-PE films with grafting density from 10 to 30 mug/cm(2). On the other hand, a dense apatite layer with some cracks was coated when the grafting density of the PAAc chains was over 30 mug/cm(2). These results indicated that it was possible to coat apatite on hydrophilic polymer grafted PE films by an alternate soaking process and that the apatite crystal morphology could be controlled as a function of polymer type and density. (C) 2000 Elsevier Science Ltd. All rights reserved.