ACUTE PHASE PROTEINS, C9, FACTOR-B, AND LYSOZYME IN RECURRENT ORAL ULCERATION AND BEHCETS SYNDROME

ACUTE PHASE PROTEINS, C9, FACTOR-B, AND LYSOZYME IN RECURRENT ORAL ULCERATION AND BEHCETS SYNDROME
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DOI:
10.1136/jcp.33.3.269
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发表时间:
1980-01-01
影响因子:
3.4
通讯作者:
ADINOLFI, M
ADINOLFI, M
中科院分区:
医学3区
文献类型:
--
作者:
LEHNER, T;ADINOLFI, M

文献摘要

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本文测定了复发性口腔溃疡和白塞综合征患者急性时相蛋白、B因子和溶菌酶的含量及其动态变化。C9 [补体成分9]在两组患者中均升高,并且是疾病活动性的最敏感指标:它不能区分3种类型的复发性口腔溃疡和4种类型的白塞综合征。α 1酸性糖蛋白和溶菌酶的水平主要在眼型中显著增加;因子B显著增加,尤其是在神经型白塞综合征中。一些血浆蛋白浓度的变化可能有助于了解白塞氏综合征的组织受累情况以及该疾病治疗药物的选择。
The concentrations and sequential changes of some acute phase proteins, factor B and lysozyme were assayed in recurrent oral ulceration and Behcet''s syndrome. C9 [complement component 9] was elevated in both groups of patients and was the most sensitive index of disease activity: it failed to discriminate between the 3 types of recurrent oral ulcers and 4 types of Behcet''s syndrome. The level of .alpha.1 acid glycoprotein and lysozyme was significantly increased predominantly in the ocular type; factor B was significantly increased especially in the neurological type of Behcet''s syndrome. The changes in the concentrations of some plasma proteins may help in understanding the tissue involvement in Behcet''s syndrome and in the selection of therapeutic agents in this disease.