A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection
A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection
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DOI：
10.1039/d0an00704h
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发表时间：
2020-08-07
期刊：
影响因子：
4.2
通讯作者：
Li, XiuJun
中科院分区：
文献类型：
--
作者：
Prasad, K. Sudhakara;Abugalyon, Yousef;Li, XiuJun
首次报道了一种低成本、灵敏、一次性纸基免疫传感器，用于胰腺癌生物标志物PEAK 1的无仪器比色检测，其利用了金纳米颗粒在彩色染料降解中的催化性能。这种简单的信号放大方法使检测灵敏度提高了约10倍。
A low-cost, sensitive, and disposable paper-based immunosensor for instrument-free colorimetric detection of pancreatic cancer biomarker PEAK1 was reported for the first time by capitalizing the catalytic properties of gold nanoparticles in colour dye degradation. This simple signal amplification method enhances the detection sensitivity by about 10 fold.