Three Cases of Concurrent Infection with Mycobacterium tuberculosis and Cryptococcus neoformans
Three Cases of Concurrent Infection with Mycobacterium tuberculosis and Cryptococcus neoformans
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DOI：
10.2169/internalmedicine.53.1281
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发表时间：
2014-01-01
影响因子：
1.2
通讯作者：
Kohno, Shigeru
中科院分区：
文献类型：
--
作者：
Kakeya, Hiroshi;Izumikawa, Koichi;Kohno, Shigeru
细胞免疫功能受损是结核病和隐球菌病的已知危险因素。然而，与肺结核相关的肺隐球菌病是罕见的。我们在此描述三例同时感染结核分枝杆菌和新生隐球菌的病例。所有患者都有潜在疾病；所有三人都有未得到控制的糖尿病，其他潜在疾病是需要长期使用类固醇的肝硬变、恶性肿瘤和类风湿性关节炎。我们还审查了其他相关报告。
Impaired cellular-mediated immunity is a known risk factor for both tuberculosis and cryptococcosis. However, pulmonary cryptococcosis associated with pulmonary tuberculosis is rare. We herein describe three cases of concurrent infection with Mycobacterium tuberculosis and Cryptococcus neoformans. All patients had underlying diseases; all three had uncontrolled diabetes mellitus, and other underlying diseases were liver cirrhosis, malignancy, and rheumatoid arthritis requiring long-term steroid use. We also review other relevant reports.