Effects of conductive hearing loss on temporal aspects of sound transmission through the ear

Effects of conductive hearing loss on temporal aspects of sound transmission through the ear
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DOI:
10.1016/s0378-5955(02)00797-9
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发表时间:
2003-03-01
期刊:
影响因子:
2.8
通讯作者:
Moore, DR
Moore, DR
中科院分区:
医学1区
文献类型:
--
作者:
Hartley, DEH;Moore, DR

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传导性听力损失对听力水平和频谱的影响是众所周知的。然而,鲜为人知的是可能的额外影响的时间方面的声音传输。本研究探讨了耳塞和中耳积液对沙土鼠耳蜗微音(CM)反应幅度和时间的影响。在(i)单侧耳塞插入或(ii)将不同粘度的硅油注入一只中耳之前和之后,监测对纯音(1-16 kHz)的双侧CM反应。耳塞在较低频率(平均80 μ s,1-6 kHz)下比在较高频率(20 μ s,8- 1-6 kHz)下产生平坦听力损失(平均13 dB)和延迟CM。渗出液也会导致平坦听力损失。平均而言,高粘度积液产生的听力损失(36分贝)大于中等(25分贝)或低(20分贝)粘度积液。低粘度和中等粘度积液延迟响应较低(平均82和65 μ s,分别为1-6 kHz)比高(平均20和10 μ s,分别为8- 1 - 6 kHz)频率。高粘度渗出液在所有频率(平均31 μ s,1-16 kHz)产生较小的延迟。在正常动物中,CM反应在很宽的刺激水平范围内没有延迟。因此,除了衰减之外,传导损耗还使对听力重要的声学时间线索失真。(C)2003 Elsevier Science B. V.保留所有权利。
Effects of conductive hearing loss on level and spectrum are well known. However, little is known about possible additional effects on temporal aspects of sound transmission. This study investigated effects of earplugs and middle ear effusions on amplitude and timing of cochlear microphonic (CM) responses in gerbils. Bilateral CM responses to pure tones (1-16 kHz) were monitored before and after (i) unilateral earplug insertion or (ii) injection of silicone oil, of various viscosities, into one middle ear. Earplugs produced flat hearing losses (mean 13 dB) and delayed CMs more at lower (mean 80 mus, 1-6 kHz) than at higher (20 mus, 8-16 kHz) frequencies. Effusions also produced flat hearing loss. On average, high viscosity effusions produced larger hearing losses (36 dB) than medium (25 dB) or low (20 dB) viscosity effusions. Low and medium viscosity effusions delayed responses to lower (mean 82 and 65 mus respectively, 1-6 kHz) more than to higher (mean 20 and 10 mus respectively, 8-16 kHz) frequencies. High viscosity effusions produced smaller delays across all frequencies (mean 31 mus, 1-16 kHz). In normal animals, CM responses were not delayed over a wide range of stimulus levels. Therefore, in addition to attenuation, conductive loss distorts acoustic temporal cues important for hearing. (C) 2003 Elsevier Science B.V. All rights reserved.