Binary nature and radiographic identifiability of craniosynostosis.
Binary nature and radiographic identifiability of craniosynostosis.
复制标题
颅缝早闭的二元性质和放射学可识别性。
DOI：
10.1097/00004424-199410000-00005
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发表时间：
1994
影响因子：
6.7
通讯作者：
Hardesty,RA
中科院分区：
文献类型：
--
作者：
Pilgram,TK;Vannier,MW;Marsh,JL;Kraemer,BB;Rayne,SC;Gado,MH;Moran,CJ;McAlister,WH;Shackelford,GD;Hardesty,RA
首页--期刊主要分类--期刊细介绍--期刊题录与文摘--期刊详细文摘内容颅缝融合的二值性和放射学可识别性。比率和目的：采用两种独立的金标准和来自三维计算机断层扫描(CT)图像的诊断，以检验颅缝融合是一种可能被正确诊断的二元异常的可能性。方法：比较25例接受颅缝融合手术治疗的儿童的手术报告、切除的缝合线的组织学和三维CT图像。手术报告将缝合分为正常或异常。组织学报告缝合闭合程度为5分。四位放射科医生使用三维CT图像对缝合线进行6分等级的诊断。结果：手术报告中组织学为0、1或2的缝合线为正常，组织学为3或4的为异常。大多数读者都达到了近乎完美的灵敏度和特异度。读者的可信度与病理程度无关。结论：在我们的样本中，颅骨融合症似乎是二元的。经验丰富的观众阅读的手术报告、病理结果和三维CT图像几乎完全一致。
Pilgram TK, Vannier MW, Marsh JL, Kraemer BB, Rayne SC, Gado MH, Moran CJ, McAlister WH, Shackelford GD, Hardesty RA. Binary nature and radiographic identifiability of craniosynostosis.RATIONALE AND OBJECTIVES.Two independent gold standards and diagnoses from three-dimensional computed tomography (CT) images were used to examine the possibility that craniosynostosis is a binary abnormality that potentially may be diagnosed without error.METHODS.Surgical reports, histology of excised sutures, and three-dimensional CT images were compared for 25 children undergoing surgical management of craniosynostosis. Surgical reports identified sutures as normal or abnormal. Histology reported suture closure on a 5-point scale. Four radiologists used three-dimensional CT images to diagnose sutures on a 6-point rated response scale.RESULTS.Sutures with histology 0, 1, or 2 were normal on surgical reports, and those with histology 3 or 4 were abnormal. Most readers achieved nearly perfect sensitivity and specificity. Reader confidence was unrelated to degree of pathology.CONCLUSION.Craniosynostosis appears to be binary in our sample. Surgical reports, pathology results, and three-dimensional CT images read by experienced viewers achieved nearly perfect agreement.