[Assessment of extracellular fluid in cardiac surgery using cardiopulmonary bypass].
[Assessment of extracellular fluid in cardiac surgery using cardiopulmonary bypass].
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[体外循环心脏手术中细胞外液的评估]。
DOI：
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发表时间：
2003
影响因子：
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通讯作者：
M. Kadota
中科院分区：
文献类型：
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作者：
Y. Hamada;K. Kawachi;N. Tsunooka;Y. Nakamura;S. Takano;H. Imagawa;M. Kadota
使用体外循环（CPB）进行心脏手术之前和之后评估细胞外液（ECF），通过生物阻抗频谱分析仪根据不同频率的阻抗变化来查看液体体积。将手术前后的水平差异除以体重来研究％BW。同时研究其与肺顺应性[潮气量/(吸气峰值压-呼气末压力)]的关系。 18 名患者的平均年龄为 59.1 +/- 19 岁。术前至术后24小时连续评估ECF，48小时后再次评估。平均 CPB 时间为 165 +/- 52 分钟，主动脉交叉钳夹时间为 121 +/- 4 分钟。术后立即观察到ECF显着增加，并进一步逐渐增加，直至术后4小时达到峰值（4.52+/-1.8%BW）。 48 小时后逐渐下降至 0.641 +/- 2.7% BW。同时测量的肺顺应性在术后6小时达到最低水平。据了解，生物阻抗谱分析是一种简单、无创的方法，可以监测手术前后的生命稳定性。
Extracellular fluid (ECF) was assessed before and after the cardiac surgery using cardiopulmonary bypass (CPB), by means of a bioimpedance spectrum analyzer to see volumes of the fluid based on changes of the impedance to various frequencies. Difference between the levels before and after the operation was divided by body weight to study about a % BW. Simultaneously its relation to the lung compliance [tidal volume/(peak inspiratory pressure-end expiratory pressure)] was studied. Mean age of the 18 patients was 59.1 +/- 19 years old. ECF was assessed before to 24 hours after the operation continuously and once more after 48 hours. Mean CPB time was 165 +/- 52 minutes, and aortic cross clamp time was 121 +/- 4 minutes. A remarkable increase of ECF was noted immediately after the operation, which further increased gradually till arriving at the peak 4 hours after the operation (4.52 +/- 1.8% BW). Then it gradually decreased to 0.641 +/- 2.7% BW 48 hours later. Lung compliance measured at the same time showed the lowest level 6 hours after the operation. It was known that the bioimpedance spectrum analysis is a simple and non-invasive method, which enables to monitor the vital stable before and after the operation.