ENGRAILED - A GENE CONTROLLING COMPARTMENT AND SEGMENT FORMATION IN DROSOPHILA
ENGRAILED - A GENE CONTROLLING COMPARTMENT AND SEGMENT FORMATION IN DROSOPHILA
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DOI：
10.1073/pnas.78.2.1095
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发表时间：
1981-01-01
期刊：
影响因子：
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通讯作者：
KORNBERG, T
中科院分区：
文献类型：
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作者：
KORNBERG, T
共分离出58个在该错切位点的突变。这个基因位点显然是生存所必需的，但只在后室的细胞中需要。失活的爬行基因座使动物不能保持细胞群之间的分离，这些细胞群构成细分每个节段的隔室或单个节段本身。
A total of 58 mutations at the engrailed locus were isolated. This genetic locus evidently is necessary for survival but required only in the cells of the posterior compartments. Inactivation of the engrailed locus renders the animal incapable of maintaining the separation between the groups of cells that constitute either the compartments that subdivide each segment, or the individual segments themselves.