Diffusion-weighted magnetic resonance imaging in Marchiafava-Bignami disease: follow-up studies
Diffusion-weighted magnetic resonance imaging in Marchiafava-Bignami disease: follow-up studies
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DOI：
10.1007/s00234-005-1368-6
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发表时间：
2005-07-01
期刊：
影响因子：
2.8
通讯作者：
Cotton, F
中科院分区：
文献类型：
--
作者：
Hlaihel, C;Gonnaud, PM;Cotton, F
marchiafva - bignami病（MBD）是一种酒精中毒患者的急性中毒性胼胝体脱髓鞘，在大多数患者中与进化不良相关。我们在此报告两例MBD患者的早期和晚期扩散磁共振成像（MRI）和表观扩散系数（ADC）研究，结果良好。弥散和解剖MRI变化与临床进展平行，提示MRI研究有助于诊断和随访。与中风不同，ADC图上的受限扩散似乎不是不可逆性的标志。
Marchiafava-Bignami disease (MBD), an acute toxic demyelination of the corpus callosum in alcoholics, is associated with poor evolution in the majority of patients. We report here the early and late diffusion magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) studies of two patients suffering from MBD with favourable outcome. Diffusion and anatomical MRI changes were parallel to the clinical evolution, suggesting that MRI studies can be helpful for diagnosis and follow-up. Unlike in stroke, restricted diffusion on ADC maps does not seem to be a sign of irreversibility.