Receiver operating characteristic analysis of aerodynamic parameters obtained by airflow interruption: A preliminary report
Receiver operating characteristic analysis of aerodynamic parameters obtained by airflow interruption: A preliminary report
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DOI：
10.1177/000348940411301205
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发表时间：
2004-12-01
影响因子：
1.4
通讯作者：
Stern, J
中科院分区：
文献类型：
--
作者：
Jiang, J;Stern, J
空气动力学参数提供了喉功能状态的客观和定量测量。Jiang等人先前介绍了一种气流中断技术，可以确定平均发声气流、舌下压。和发声阈值压力。在这项研究中，我们进行了受试者工作特性（ROC）分析，以评估这种气流中断装置的声音轮廓分析与喉息肉或结节或帕金森氏病。患者息肉（n = 14），结节（n = 9），帕金森病（12）进行了评估与气流中断装置。正常受试者作为对照。平均气流声门下压。和发声阈压。判别分析用于创建组合所有三个参数的线性方程，以获得新的组合参数。线性方程组的解决方案产生的值的组合参数，考虑到平均值，气流，球囊下的压力，发声阈值压力。使用组合参数值作为数据以生成ROC曲线。鉴别喉息肉与正常喉的灵敏度为0.929，特异度为0.933。ROC曲线下面积为0.977（Az）。帕金森病患者与正常人区分的敏感性为0.667，特异性为0.909，在最大效率点。ROC曲线下面积为0.7958（Az）。结节能够区分与正常的敏感性为0.889和特异性为1.00。ROC曲线下面积为0.9565（Az）。我们的结论是双重的。先气动力参数可以通过微分分析建立线性方程组来组合起来同时考虑。一下气流干涉装置。用于嗓音功能评价时，具有较高的灵敏度和特异性。
Aerodynamic parameters provide objective and quantitative measures of laryngeal functional status. Jiang et al previously introduced an airflow interruption technique that can determine mean phonatory airflow, subglonic pressure. and phonation threshold pressure simultaneously and noninvasively. In this study, we performed receiver operating characteristic (ROC) analysis to evaluate this airflow interruption apparatus for voice profile analysis in subjects with laryngeal polyps or nodules or with Parkinson's disease. Patients with polyps (n = 14), nodules (n = 9), and Parkinson's disease (it 12) were evaluated with the airflow interruption apparatus. Normal subjects served as controls. Mean airflow, subglottic pressure. and phonation threshold pressure were determined. Discriminant analysis was used to create linear equations combining ail three parameters in order to obtain a new combined parameter. Solutions to the linear equations yielded values for the combined parameter that took into account mean, airflow, subglonic pressure, and phonation threshold pressure. Combined parameter values were used as data to generate ROC curves. Laryngeal polyps were distinguished from the normal larynx with a sensitivity of 0.929 and a specificity of 0.933 at the point of maximal efficiency. The area under the ROC curve was 0.977 (Az). Patients with Parkinson's disease were distinguished front normal subjects with a sensitivity of 0.667 and a specificity of 0.909 at the point of maximal efficiency. The area under the ROC curve was 0.7958 (Az). Nodules were able to be distinguished from normal with a sensitivity of 0.889 and a specificity of 1.00. The area under the ROC curve was 0.9565 (Az). Our conclusions are twofold. First. aerodynamic parameters may be combined for simultaneous consideration by the construction of linear equations by means of discrinunant analysis. Second. the airflow interrupoon apparatus. when used for voice function evaluation, has high sensitivity and specificity.