THE FLUORODEOXYGLUCOSE F-18 SCAN IN ALZHEIMERS-DISEASE AND MULTI-INFARCT DEMENTIA
THE FLUORODEOXYGLUCOSE F-18 SCAN IN ALZHEIMERS-DISEASE AND MULTI-INFARCT DEMENTIA
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DOI：
10.1001/archneur.1983.04050110029003
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发表时间：
1983-01-01
影响因子：
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通讯作者：
TSAI, SY
中科院分区：
文献类型：
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作者：
BENSON, DF;KUHL, DE;TSAI, SY
用18Fl标记的氟脱氧葡萄糖扫描研究了阿尔茨海默病和多发梗死性痴呆患者。计算葡萄糖代谢率。阿尔茨海默氏痴呆症患者表现出大脑所有区域的代谢下降，但主要运动和感觉皮层优先保留。与正常对照组相比，多发梗死性痴呆患者的葡萄糖代谢率也整体降低，但代谢降低的区域是局部的和不对称的。
Patients with Alzheimer''s disease and multi-infarct dementia were studied with scans using fluorodeoxyglucose labeled with 18Fl. The rates of glucose metabolism were calculated. Patients with Alzheimer''s dementia showed decreased metabolism in all areas of the brain but with preferential sparing of the primary motor and sensory cortex. Patients with multi-infarct dementia also had global reductions in glucose metabolic rates when compared with normal control subjects, but the areas of hypometabolism were focal and asymmetric.