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DOI:
10.1111/j.1469-8749.1998.tb12369.x
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发表时间:
1998-12
影响因子:
3.8
通讯作者:
P. Gomes;S. Fernando;D. Weerasekara;V. Velathanthiri;M. Rizny;Mm;Weerasekara;R. Mahendra
P. Gomes;S. Fernando;D. Weerasekara;V. Velathanthiri;M. Rizny;Mm;Weerasekara;R. Mahendra
中科院分区:
医学2区
文献类型:
--
作者:
P. Gomes;S. Fernando;D. Weerasekara;V. Velathanthiri;M. Rizny;Mm;Weerasekara;R. Mahendra

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简介:胆结石疾病是一个主要的健康问题,在世界各地。除手术治疗外,及时应用适当的抗生素控制胆道感染也很重要。目的:阐明胆石病的细菌学特点。设计图:将接受胆囊切除术的有症状胆囊疾病患者的胆结石和胆汁在血琼脂和麦康凯琼脂中需氧培养一年以上。未进行富集,因为在先前的研究中未指出。根据标准微生物学程序鉴定分离株,并检测其敏感性模式。设置:微生物学系,斯里兰卡卡卢博维拉的斯里兰卡贾亚瓦德纳普拉大学和科隆博南教学医院。结果:20%的患者胆汁或结石细菌阳性。大肠埃希菌(40%)、克雷伯菌属(35%)和肠杆菌属(20%)是最常见的分离株。大肠菌群占所有分离株的91%。结论:我们建议在胆囊切除术时进行胆汁和胆结石的培养,以便在培养阳性的情况下给予适当的抗生素
Introduction: Gallstone disease is a major health problem throughout the world. Apart from surgery prompt administration of appropriate antibiotics to control the biliary tract infection is important. Objective: Illustrate the bacteriology of gallstone disease. Design: The bile stones and bile of patients with symptomatic gallbladder disease, who underwent cholecystectomy, over a period of one year, were cultured aerobically in blood agar and MacConkey agar. Enrichment was not done, as it was not indicated in previous studies. The isolates were identified according to standard microbiological procedures and were tested for their sensitivity pattern. Settings: Department of Microbiology, University of Sri Jayawardenapura and Colombo South Teaching Hospital, Kalubowila, Sri Lanka. Results: Twenty percent of the patients were positive for bacteria in either bile or stones. Escherichia coli (40%), Klebsiella spp (35%) and Enterobacter spp (20%) were the commonest isolates. Ninety one percent of all isolates were Coliforms. Conclusions: We recommend obtaining of cultures of bile and gallstones at the time of cholecystectomy so that appropriate antibiotics can be administered in the event of a positive culture