Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial

Novel glucose-sensing technology and hypoglycaemia in type 1 diabetes: a multicentre, non-masked, randomised controlled trial
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DOI:
10.1016/s0140-6736(16)31535-5
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发表时间:
2016-11-05
期刊:
影响因子:
168.9
通讯作者:
Weitgasser, Raimund
Weitgasser, Raimund
中科院分区:
医学1区
文献类型:
--
作者:
Bolinder, Jan;Antuna, Ramiro;Weitgasser, Raimund

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背景1型糖尿病患者严格控制血糖可延迟大血管和微血管糖尿病并发症的发生;然而,需要密切监测血糖水平以预防低血糖。我们的目的是评估是否工厂校准,传感器为基础,闪光葡萄糖监测系统相比,自我监测血糖检测降低暴露于低血糖的1型糖尿病患者。方法在这个多中心,前瞻性,非盲,随机对照试验,我们招募了成年患者控制良好的1型糖尿病(HbA(1c))
Background Tight control of blood glucose in type 1 diabetes delays onset of macrovascular and microvascular diabetic complications; however, glucose levels need to be closely monitored to prevent hypoglycaemia. We aimed to assess whether a factory-calibrated, sensor-based, flash glucose-monitoring system compared with self-monitored glucose testing reduced exposure to hypoglycaemia in patients with type 1 diabetes.Methods In this multicentre, prospective, non-masked, randomised controlled trial, we enrolled adult patients with well controlled type 1 diabetes (HbA(1c)