Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson's Disease: A Review.
Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson's Disease: A Review.
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DOI：
10.3390/molecules25173926
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发表时间：
2020-08-27
期刊：
影响因子：
--
通讯作者：
Tencomnao T
中科院分区：
文献类型：
--
作者：
Malar DS;Prasanth MI;Brimson JM;Sharika R;Sivamaruthi BS;Chaiyasut C;Tencomnao T
神经退行性疾病是对临床症状的统称，它会导致神经元的进行性退化和与受影响的大脑区域相关的功能丧失。除了年龄的增加，神经退行性疾病也在一定程度上受到饮食和生活方式的影响。帕金森病(PD)是一种慢性起病的神经退行性疾病，是影响运动系统的第二常见神经退行性疾病。虽然没有预防和治愈帕金森氏症的处方治疗方法，但临床程序有助于控制疾病症状。绿茶多酚对健康有多种益处，包括抗氧化、抗炎和神经保护活性。目前的手稿总结了绿茶可能的神经保护作用机制，特别是对帕金森病的关注。研究表明，饮用绿茶可以预防自由基、炎症和神经损伤。几项体内研究有助于理解绿茶的整体机制。然而，由于复杂的生理、社会和文化发展，同样的剂量可能不足以在人类身上引起类似的影响。未来的研究将重点放在更多的临床试验上，以确定最优剂量，从而最大限度地保护帕金森病患者的健康。
Neurodegenerative disease is a collective term given for the clinical condition, which results in progressive degeneration of neurons and the loss of functions associated with the affected brain region. Apart from the increase in age, neurodegenerative diseases are also partly affected by diet and lifestyle practices. Parkinson’s disease (PD) is a slow onset neurodegenerative disorder and the second most common neurodegenerative disease, which affects the motor system. Although there is no prescribed treatment method to prevent and cure PD, clinical procedures help manage the disease symptoms. Green tea polyphenols are known for several health benefits, including antioxidant, anti-inflammatory, and neuroprotective activity. The current manuscript summarizes the possible mechanisms of neuroprotective potential of green tea with a special focus on PD. Studies have suggested that the consumption of green tea protects against free-radicals, inflammation, and neuro-damages. Several in vivo studies aid in understanding the overall mechanism of green tea. However, the same dose may not be sufficient in humans to elicit similar effects due to complex physiological, social, and cultural development. Future research focused on more clinical trials could identify an optimum dose that could impart maximum health benefits to impart neuroprotection in PD.
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影响因子：
9.9
作者：
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通讯作者：
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影响因子：
1.5
作者：
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作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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DOI：
10.1007/s10534-013-9681-8
发表时间：
2013-12
期刊：
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
影响因子：
--
作者：
Bao GH;Xu J;Hu FL;Wan XC;Deng SX;Barasch J
通讯作者：
Barasch J