Outpatient antibiotic use in British Columbia, Canada: reviewing major trends since 2000.

Outpatient antibiotic use in British Columbia, Canada: reviewing major trends since 2000.
复制标题

加拿大不列颠哥伦比亚省门诊抗生素使用:回顾2000年以来的主要趋势。

DOI:
10.1093/jacamr/dlab116
复制
发表时间:
2021-09
影响因子:
3.4
通讯作者:
Marra F
Marra F
中科院分区:
其他
文献类型:
--
作者:
Saatchi A;Morris AM;Patrick DM;Mccormack J;Reyes RC;Morehouse P;Reid J;Shariff S;Povitz M;Silverman M;Marra F

文献摘要

参考文献

被引文献

相似文献

由于加拿大90%的抗生素都是在社区环境中使用的,因此跟踪门诊处方对于缓解抗生素耐药性问题至关重要。2005年,不列颠哥伦比亚省启动了一项省级方案,以传播关于合理使用抗生素的信息。这些努力包括教育活动,更新从业人员指南和学术细节。省级管理对社区处方的影响需要持续评估。这项研究检查了门诊处方,以量化抗生素使用率,评估随着时间的推移的主要趋势,并确定新的管理目标。使用人群水平数据的回顾性队列设计。这项研究包括超过350万个独特的个人,在19年的时间内(2000-18)共分发了51367 938份口服抗生素处方。 在研究期间,抗生素的总体使用率下降了23%。在所有主要抗生素类别中均观察到抗生素处方减少的趋势,但其他抗菌药物类别除外,这主要与呋喃妥因的使用有关。在儿科人群中观察到处方减少幅度最大。与抗生素使用的管理前水平相比,在两个不同的省级管理时代开处方重申了项目有效性的初步结果。BC省的门诊处方总体上正在减少,这项研究证实了省级管理干预与抗生素使用改善之间的关联。儿科人群的显著下降是有希望的,进一步的研究正在进行中,以检查处方质量。
With 90% of all antibiotics in Canada being used in the community setting, tracking outpatient prescribing is integral to mitigate the issue of antimicrobial resistance. In 2005, a provincial programme was launched in British Columbia (BC) to disseminate information regarding the judicious use of antibiotics. These efforts include educational campaigns, updated practitioner guidelines and academic detailing. The impact of provincial stewardship on community prescribing requires ongoing evaluation. This study examines outpatient prescribing to quantify rates of antibiotic use, evaluate major trends over time and identify new targets for stewardship. A retrospective cohort design using population-level data. This study included over 3.5 million unique individuals with a total of 51 367 938 oral antibiotic prescriptions dispensed over a 19 year period (2000–18). Overall antibiotic utilization decreased by 23% over the course of the study period. This trend in the reduction of antibiotic prescription was observed across all major antibiotic classes, apart from the class of other antibacterials, which was mostly related to use of nitrofurantoin. The largest magnitudes of decreased prescribing were observed in the paediatric population. Prescribing across two distinct eras of provincial stewardship reaffirmed preliminary findings of programme efficacy, when compared with pre-stewardship levels of antibiotic use. Outpatient prescribing in BC is decreasing overall, and this study confirms an association between provincial stewardship interventions and improvements in antibiotic use. Pronounced declines in paediatric populations are promising, and further research is underway to examine prescribing quality.
DOI: 10.1093/jac/dks445
发表时间: 2013-03-01
影响因子: 5.2
作者:
Suda, Katie J.;Hicks, Lauri A.;Danziger, Larry H.
通讯作者: Danziger, Larry H.
DOI: 10.1155/2011/745090
发表时间: 2011-03-01
影响因子: 2.8
作者:
McKay, Rachel M.;Vrbova, Linda;Patrick, David M.
通讯作者: Patrick, David M.
DOI: 10.1093/cid/cis370
发表时间: 2012-04-15
影响因子: 11.8
作者:
Chow, Anthony W.;Benninger, Michael S.;File, Thomas M., Jr.
通讯作者: File, Thomas M., Jr.
DOI: 10.1001/jama.2016.4151
发表时间: 2016-05-03
影响因子: 120.7
作者:
Fleming-Dutra, Katherine E.;Hersh, Adam L.;Hicks, Lauri A.
通讯作者: Hicks, Lauri A.
DOI: 10.9778/cmajo.20190175
发表时间: 2020-04-01
期刊: CMAJ open
影响因子: --
作者:
Schwartz, Kevin L;Langford, Bradley J;Garber, Gary
通讯作者: Garber, Gary