SCHISTOSOMIASIS HAEMATOBIA IN COAST PROVINCE KENYA - RELATIONSHIP BETWEEN EGG OUTPUT AND MORBIDITY

SCHISTOSOMIASIS HAEMATOBIA IN COAST PROVINCE KENYA - RELATIONSHIP BETWEEN EGG OUTPUT AND MORBIDITY
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DOI:
10.4269/ajtmh.1979.28.864
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发表时间:
1979-01-01
影响因子:
3.3
通讯作者:
SIONGOK, TKA
SIONGOK, TKA
中科院分区:
医学4区
文献类型:
--
作者:
WARREN, KS;MAHMOUD, AAF;SIONGOK, TKA

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非洲血吸虫病 [Schistosoma haematobium] 的几项研究揭示了通过尿虫卵计数测量的感染强度与通过静脉注射确定的疾病严重程度之间的相关性。肾盂造影。对肯尼亚沿海地区 390 名学童进行的一项调查涉及单个卵子计数和静脉注射。对 69 名儿童的分层随机样本进行的肾盂造影显示,感染强度较高的儿童泌尿道疾病的患病率较高。这项调查之后进行了一项更详细的研究,对 121 名儿童进行了连续 9 天的卵子计数;其中 17 名儿童被分为 3 组,感染程度不同,接受静脉注射。肾盂造影。 11 名具有最低和中等计数(平均每天每 10 毫升尿液分别少于 1 个卵和 167 个卵)的儿童的结果相似,其中大约 30% 存在膀胱或肾脏异常。 6 名计数较多的儿童(平均每天 1,288 个卵/10 毫升尿液)均患有膀胱病变,其中 5 名患有肾脏病变。
Several studies of schistosomiasis hematobia [Schistosoma haematobium] in Africa have revealed a correlation between intensity of infection as measured by urine egg counts and severity of disease as determined by i.v. pyelography. A survey of 390 school children in the coastal area of Kenya involving a single egg count, and i.v. pyelograms in a stratified random sample of 69 children showed a greater prevalence of urinary tract disease in those with higher intensities of infection. This survey was then followed by a more detailed study in which 9 consecutive daily egg counts were done on 121 children; 17 of these children, subdivided into 3 groups with different intensities of infection, were given i.v. pyelograms. The results were similar in the 11 children with minimal and moderate counts (averaging, respectively, < 1 egg and 167 eggs/10 ml urine daily), with approximately 30% having bladder or renal abnormalities. All of the 6 children with heavy counts (averaging 1,288 eggs/10 ml urine daily) had bladder lesions and 5 of them had renal lesions.